PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Pvir09KG0052670.1 panicum_virgatum Pvir09KG0052670.1
Pvir09KG0052670.2 panicum_virgatum Pvir09KG0052670.2
Pvir09NG0052280.1 panicum_virgatum Pvir09NG0052280.1
Papaver_setigerum_Pse02G26230.0 papaver_setigerum Papaver_setigerum_Pse02G26230.0
Papaver_setigerum_Pse03G39340.0 papaver_setigerum Papaver_setigerum_Pse03G39340.0
Papaver_setigerum_Pse04G27230.0 papaver_setigerum Papaver_setigerum_Pse04G27230.0
Papaver_setigerum_Pse05G40830.0 papaver_setigerum Papaver_setigerum_Pse05G40830.0
Papaver_setigerum_Pse07G52390.0 papaver_setigerum Papaver_setigerum_Pse07G52390.0
Papaver_setigerum_Pse10G38480.0 papaver_setigerum Papaver_setigerum_Pse10G38480.0
Papaver_setigerum_Pse10G38540.0 papaver_setigerum Papaver_setigerum_Pse10G38540.0
Papaver_setigerum_Pse11G47570.0 papaver_setigerum Papaver_setigerum_Pse11G47570.0
Papaver_setigerum_Pse12G33680.0 papaver_setigerum Papaver_setigerum_Pse12G33680.0
Papaver_setigerum_Pse13G40450.0 papaver_setigerum Papaver_setigerum_Pse13G40450.0
Papaver_setigerum_Pse14G32220.0 papaver_setigerum Papaver_setigerum_Pse14G32220.0
Papaver_setigerum_Pse17G20570.0 papaver_setigerum Papaver_setigerum_Pse17G20570.0
Papaver_setigerum_Pse18G29970.0 papaver_setigerum Papaver_setigerum_Pse18G29970.0
Papaver_setigerum_Pse20G14700.0 papaver_setigerum Papaver_setigerum_Pse20G14700.0
Papaver_setigerum_Pse20G34460.0 papaver_setigerum Papaver_setigerum_Pse20G34460.0
Papaver_setigerum_Pse21G08280.0 papaver_setigerum Papaver_setigerum_Pse21G08280.0
Psom03G0016670.1 papaver_somniferum Psom03G0016670.1
Psom05G0027920.1 papaver_somniferum Psom05G0027920.1
Psom06G0020160.1 papaver_somniferum Psom06G0020160.1
Psom07G0011870.1 papaver_somniferum Psom07G0011870.1
Psom09G0008080.1 papaver_somniferum Psom09G0008080.1
PeneHiC_scaffold_40220750 paraleucobryum_enerve PeneHiC_scaffold_40220750
PeneHiC_scaffold_80340320 paraleucobryum_enerve PeneHiC_scaffold_80340320
paulownia_fortunei_KAI3445845.1 paulownia_fortunei paulownia_fortunei_KAI3445845.1
paulownia_fortunei_KAI3446264.1 paulownia_fortunei paulownia_fortunei_KAI3446264.1
paulownia_fortunei_KAI3447935.1 paulownia_fortunei paulownia_fortunei_KAI3447935.1
paulownia_fortunei_KAI3448206.1 paulownia_fortunei paulownia_fortunei_KAI3448206.1