PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
panax_quinquefolius_GWHPBEIR023545.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR023545.1
panax_quinquefolius_GWHPBEIR041896.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR041896.1
panax_quinquefolius_GWHPBEIR042383.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR042383.1
panax_quinquefolius_GWHPBEIR042384.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR042384.1
panax_quinquefolius_GWHPBEIR043944.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR043944.1
panax_quinquefolius_GWHPBEIR047331.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR047331.1
panax_quinquefolius_GWHPBEIR053011.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR053011.1
panax_quinquefolius_GWHPBEIR053680.1 panax_quinquefolius panax_quinquefolius_GWHPBEIR053680.1
panax_stipuleanatus_GWHPBEIJ001643.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ001643.1
panax_stipuleanatus_GWHPBEIJ004043.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004043.1
panax_stipuleanatus_GWHPBEIJ004187.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004187.1
panax_stipuleanatus_GWHPBEIJ004191.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004191.1
panax_stipuleanatus_GWHPBEIJ004197.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004197.1
panax_stipuleanatus_GWHPBEIJ004199.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004199.1
panax_stipuleanatus_GWHPBEIJ004200.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004200.1
panax_stipuleanatus_GWHPBEIJ004201.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004201.1
panax_stipuleanatus_GWHPBEIJ004202.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004202.1
panax_stipuleanatus_GWHPBEIJ004741.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ004741.1
panax_stipuleanatus_GWHPBEIJ011009.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ011009.1
panax_stipuleanatus_GWHPBEIJ012965.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ012965.1
panax_stipuleanatus_GWHPBEIJ026843.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ026843.1
panax_stipuleanatus_GWHPBEIJ029865.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ029865.1
panax_stipuleanatus_GWHPBEIJ030082.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ030082.1
panax_stipuleanatus_GWHPBEIJ038776.1 panax_stipuleanatus panax_stipuleanatus_GWHPBEIJ038776.1
Phal02G0031330.1 panicum_hallii Phal02G0031330.1
Phal09G0047760.1 panicum_hallii Phal09G0047760.1
Pmil01G0047260.1 panicum_miliaceum Pmil01G0047260.1
Pmil04G0043310.1 panicum_miliaceum Pmil04G0043310.1
Pmil15G0027240.1 panicum_miliaceum Pmil15G0027240.1
Pvir09KG0033230.1 panicum_virgatum Pvir09KG0033230.1