PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
populus_ilicifolia_GWHPABKR024643 populus_ilicifolia populus_ilicifolia_GWHPABKR024643
populus_ilicifolia_GWHPABKR028790 populus_ilicifolia populus_ilicifolia_GWHPABKR028790
populus_ilicifolia_GWHPABKR028794 populus_ilicifolia populus_ilicifolia_GWHPABKR028794
populus_ilicifolia_GWHPABKR032553 populus_ilicifolia populus_ilicifolia_GWHPABKR032553
populus_ilicifolia_GWHPABKR033558 populus_ilicifolia populus_ilicifolia_GWHPABKR033558
populus_ilicifolia_GWHPABKR033635 populus_ilicifolia populus_ilicifolia_GWHPABKR033635
Ppruscaffold1353920023000 populus_pruinosa Ppruscaffold1353920023000
Ppruscaffold1358110024890 populus_pruinosa Ppruscaffold1358110024890
Ppruscaffold1390990043660 populus_pruinosa Ppruscaffold1390990043660
Ppruscaffold1390990043680 populus_pruinosa Ppruscaffold1390990043680
Ppruscaffold15730071600 populus_pruinosa Ppruscaffold15730071600
Ppruscaffold1750090560 populus_pruinosa Ppruscaffold1750090560
Ppruscaffold226950131380 populus_pruinosa Ppruscaffold226950131380
Ppruscaffold25890153530 populus_pruinosa Ppruscaffold25890153530
Ppruscaffold4220210050 populus_pruinosa Ppruscaffold4220210050
Ppruscaffold479420224780 populus_pruinosa Ppruscaffold479420224780
Ppruscaffold58980255250 populus_pruinosa Ppruscaffold58980255250
Ppruscaffold58980255260 populus_pruinosa Ppruscaffold58980255260
Ppruscaffold58980255280 populus_pruinosa Ppruscaffold58980255280
Ppruscaffold6410264920 populus_pruinosa Ppruscaffold6410264920
Potra000689g05354.1 populus_tremula Potra000689g05354.1
Potra000874g07027.2 populus_tremula Potra000874g07027.2
Potra000874g07027.3 populus_tremula Potra000874g07027.3
Potra001124g09914.1 populus_tremula Potra001124g09914.1
Potra001124g09914.2 populus_tremula Potra001124g09914.2
Potra001169g10127.1 populus_tremula Potra001169g10127.1
Potra001308g11238.1 populus_tremula Potra001308g11238.1
Potra001308g11238.2 populus_tremula Potra001308g11238.2
Potra001308g11238.3 populus_tremula Potra001308g11238.3
Potra001888g15033.1 populus_tremula Potra001888g15033.1