PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
PruarS.1G578900.t1.p1_1 prunus_armeniaca PruarS.1G578900.t1.p1_1
PruarS.6G316600.t1.p1_1 prunus_armeniaca PruarS.6G316600.t1.p1_1
PruarS.8G246300.t1.p1_1 prunus_armeniaca PruarS.8G246300.t1.p1_1
PruarS.8G246300.t2.p1_1 prunus_armeniaca PruarS.8G246300.t2.p1_1
PruarS.8G246400.t1.p1_1 prunus_armeniaca PruarS.8G246400.t1.p1_1
PruarS.8G246400.t2.p1_1 prunus_armeniaca PruarS.8G246400.t2.p1_1
PruarS.8G246500.t1.p1_1 prunus_armeniaca PruarS.8G246500.t1.p1_1
Pav_sc0000568.1_g410.1.mk:mrna prunus_avium Pav_sc0000568.1_g410.1.mk:mrna
Pav_sc0000568.1_g420.1.mk:mrna prunus_avium Pav_sc0000568.1_g420.1.mk:mrna
Pav_sc0000568.1_g440.1.mk:mrna prunus_avium Pav_sc0000568.1_g440.1.mk:mrna
Pav_sc0000568.1_g540.1.mk:mrna prunus_avium Pav_sc0000568.1_g540.1.mk:mrna
Pav_sc0000623.1_g010.1.br:CDS:1 prunus_avium Pav_sc0000623.1_g010.1.br:CDS:1
Pav_sc0005509.1_g120.1.mk:mrna prunus_avium Pav_sc0005509.1_g120.1.mk:mrna
Pav_sc0007209.1_g120.1.mk:mrna prunus_avium Pav_sc0007209.1_g120.1.mk:mrna
Pav_sc0010595.1_g010.1.mk:mrna prunus_avium Pav_sc0010595.1_g010.1.mk:mrna
Pav_sc0010863.1_g010.1.br:mrna prunus_avium Pav_sc0010863.1_g010.1.br:mrna
prunus_campanulata_evm.model.Chr01.4334 prunus_campanulata prunus_campanulata_evm.model.Chr01.4334
prunus_campanulata_evm.model.Chr06.2347 prunus_campanulata prunus_campanulata_evm.model.Chr06.2347
prunus_campanulata_evm.model.Chr08.1104 prunus_campanulata prunus_campanulata_evm.model.Chr08.1104
prunus_campanulata_evm.model.Chr08.1105 prunus_campanulata prunus_campanulata_evm.model.Chr08.1105
prunus_domestica_Pd.00g1050640.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1050640.m01-v1.0
prunus_domestica_Pd.00g1050650.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1050650.m01-v1.0
prunus_domestica_Pd.00g1050660.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1050660.m01-v1.0
prunus_domestica_Pd.00g1086470.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1086470.m01-v1.0
prunus_domestica_Pd.00g1131220.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1131220.m01-v1.0
prunus_domestica_Pd.00g1168890.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1168890.m01-v1.0
prunus_domestica_Pd.00g120390.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g120390.m01-v1.0
prunus_domestica_Pd.00g1217240.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1217240.m01-v1.0
prunus_domestica_Pd.00g1245830.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g1245830.m01-v1.0
prunus_domestica_Pd.00g376600.m01-v1.0 prunus_domestica prunus_domestica_Pd.00g376600.m01-v1.0