SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
rheum_tanguticum_RtaG0046369.1	rheum_tanguticum	rheum_tanguticum_RtaG0046369.1
rheum_tanguticum_RtaG0046893.1	rheum_tanguticum	rheum_tanguticum_RtaG0046893.1
rhizophora_apiculata_RA_17131	rhizophora_apiculata	rhizophora_apiculata_RA_17131
rhizophora_apiculata_RA_20769	rhizophora_apiculata	rhizophora_apiculata_RA_20769
rhizophora_apiculata_RA_21637	rhizophora_apiculata	rhizophora_apiculata_RA_21637
Rcrescaffold1331130027540	rhodiola_crenulata	Rcrescaffold1331130027540
Rcrescaffold1384300063820	rhodiola_crenulata	Rcrescaffold1384300063820
Rcrescaffold1385260081350	rhodiola_crenulata	Rcrescaffold1385260081350
Rcrescaffold1385390083510	rhodiola_crenulata	Rcrescaffold1385390083510
Rcrescaffold1386590095230	rhodiola_crenulata	Rcrescaffold1386590095230
Rcrescaffold1390570126000	rhodiola_crenulata	Rcrescaffold1390570126000
Rcrescaffold1390950131790	rhodiola_crenulata	Rcrescaffold1390950131790
Rcrescaffold1391450138560	rhodiola_crenulata	Rcrescaffold1391450138560
Rcrescaffold1392580151700	rhodiola_crenulata	Rcrescaffold1392580151700
Rcrescaffold175260189510	rhodiola_crenulata	Rcrescaffold175260189510
Rcrescaffold22710211370	rhodiola_crenulata	Rcrescaffold22710211370
Rdelscaffold17610059200	rhododendron_delavayi	Rdelscaffold17610059200
Rdelscaffold229540080460	rhododendron_delavayi	Rdelscaffold229540080460
Rdelscaffold229540080470	rhododendron_delavayi	Rdelscaffold229540080470
Rdelscaffold29140214990	rhododendron_delavayi	Rdelscaffold29140214990
KAG5529119.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5529119.1_rhododendron_griersonianum
KAG5535452.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5535452.1_rhododendron_griersonianum
KAG5543696.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5543696.1_rhododendron_griersonianum
KAG5548301.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5548301.1_rhododendron_griersonianum
KAG5552903.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5552903.1_rhododendron_griersonianum
KAG5553549.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5553549.1_rhododendron_griersonianum
KAG5553558.1_rhododendron_griersonianum	rhododendron_griersonianum	KAG5553558.1_rhododendron_griersonianum
rhododendron_molle_KAI8541985.1	rhododendron_molle	rhododendron_molle_KAI8541985.1
rhododendron_molle_KAI8550128.1	rhododendron_molle	rhododendron_molle_KAI8550128.1
rhododendron_molle_KAI8550129.1	rhododendron_molle	rhododendron_molle_KAI8550129.1