SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Sdon797200255240	sphaerocarpos_donnellii	Sdon797200255240
Sgircontig_290112190	sphagnum_girgensohnii	Sgircontig_290112190
Sgircontig_340129220	sphagnum_girgensohnii	Sgircontig_340129220
Sgircontig_5020181430	sphagnum_girgensohnii	Sgircontig_5020181430
Sgircontig_8200291440	sphagnum_girgensohnii	Sgircontig_8200291440
Spal2208880016510	sphagnum_palustre	Spal2208880016510
Spal2496420025510	sphagnum_palustre	Spal2496420025510
Spal3272650063730	sphagnum_palustre	Spal3272650063730
Spal3296580074120	sphagnum_palustre	Spal3296580074120
Spal3302510084050	sphagnum_palustre	Spal3302510084050
Spal3402460101030	sphagnum_palustre	Spal3402460101030
Spal3529310203690	sphagnum_palustre	Spal3529310203690
Spal3537060221760	sphagnum_palustre	Spal3537060221760
Spal3551050258870	sphagnum_palustre	Spal3551050258870
Sole06G0017290	spinacia_oleracea	Sole06G0017290
SoleSpoScf_004880010690	spinacia_oleracea	SoleSpoScf_004880010690
SoleSuper_scaffold_1750089270	spinacia_oleracea	SoleSuper_scaffold_1750089270
spirodela_intermedia_CAA7387719.1	spirodela_intermedia	spirodela_intermedia_CAA7387719.1
Spolpseudo20090700.1	spirodela_polyrhiza	Spolpseudo20090700.1
Spolpseudo30142940.1	spirodela_polyrhiza	Spolpseudo30142940.1
stellera_chamaejasme_SchT006140.1	stellera_chamaejasme	stellera_chamaejasme_SchT006140.1
stellera_chamaejasme_SchT010263.1	stellera_chamaejasme	stellera_chamaejasme_SchT010263.1
stellera_chamaejasme_SchT010696.1	stellera_chamaejasme	stellera_chamaejasme_SchT010696.1
stellera_chamaejasme_SchT010828.1	stellera_chamaejasme	stellera_chamaejasme_SchT010828.1
stellera_chamaejasme_SchT020556.1	stellera_chamaejasme	stellera_chamaejasme_SchT020556.1
stellera_chamaejasme_SchT021368.1	stellera_chamaejasme	stellera_chamaejasme_SchT021368.1
Sreb01G0015300.1	stevia_rebaudiana	Sreb01G0015300.1
Sreb02G0043700.1	stevia_rebaudiana	Sreb02G0043700.1
Sreb05G0026470.1	stevia_rebaudiana	Sreb05G0026470.1
Sreb07G0021040.1	stevia_rebaudiana	Sreb07G0021040.1