SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Sreb08G0033080.1	stevia_rebaudiana	Sreb08G0033080.1
Sreb09G0017950.1	stevia_rebaudiana	Sreb09G0017950.1
Sreb09G0018140.1	stevia_rebaudiana	Sreb09G0018140.1
Sreb09G0030930.1	stevia_rebaudiana	Sreb09G0030930.1
SrebContig005500004290.1	stevia_rebaudiana	SrebContig005500004290.1
streptocarpus_rexii_Sr00203-RA	streptocarpus_rexii	streptocarpus_rexii_Sr00203-RA
streptocarpus_rexii_Sr00241-RA	streptocarpus_rexii	streptocarpus_rexii_Sr00241-RA
streptocarpus_rexii_Sr00448-RA	streptocarpus_rexii	streptocarpus_rexii_Sr00448-RA
streptocarpus_rexii_Sr10398-RA	streptocarpus_rexii	streptocarpus_rexii_Sr10398-RA
streptocarpus_rexii_Sr19441-RA	streptocarpus_rexii	streptocarpus_rexii_Sr19441-RA
streptocarpus_rexii_Sr19442-RA	streptocarpus_rexii	streptocarpus_rexii_Sr19442-RA
streptocarpus_rexii_Sr22611-RA	streptocarpus_rexii	streptocarpus_rexii_Sr22611-RA
streptocarpus_rexii_Sr29638-RA	streptocarpus_rexii	streptocarpus_rexii_Sr29638-RA
streptocarpus_rexii_Sr35885-RA	streptocarpus_rexii	streptocarpus_rexii_Sr35885-RA
Sasiscaffold2190119240.1	striga_asiatica	Sasiscaffold2190119240.1
Sasiscaffold2380130020.1	striga_asiatica	Sasiscaffold2380130020.1
Sasiscaffold3370183960.1	striga_asiatica	Sasiscaffold3370183960.1
striga_hermonthica_CAA0812390.1	striga_hermonthica	striga_hermonthica_CAA0812390.1
striga_hermonthica_CAA0830994.1	striga_hermonthica	striga_hermonthica_CAA0830994.1
striga_hermonthica_CAA0842120.1	striga_hermonthica	striga_hermonthica_CAA0842120.1
striga_hermonthica_CAA0843335.1	striga_hermonthica	striga_hermonthica_CAA0843335.1
Scus01G0014680.1	strobilanthes_cusia	Scus01G0014680.1
Scus01G0017890.1	strobilanthes_cusia	Scus01G0017890.1
Scus01G0017900.1	strobilanthes_cusia	Scus01G0017900.1
Scus11G0002680.1	strobilanthes_cusia	Scus11G0002680.1
Scus16G0017460.1	strobilanthes_cusia	Scus16G0017460.1
Scus16G0017470.1	strobilanthes_cusia	Scus16G0017470.1
Scus16G0017480.1	strobilanthes_cusia	Scus16G0017480.1
Scus16G0017490.1	strobilanthes_cusia	Scus16G0017490.1
Scus16G0017500.1	strobilanthes_cusia	Scus16G0017500.1