SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
PNH04970.1_tsocial	tetrabaena_socialis	PNH04970.1_tsocial
KAF8404435.1	tetracentron_sinense	KAF8404435.1
KAF8404831.1	tetracentron_sinense	KAF8404831.1
KAF8406170.1	tetracentron_sinense	KAF8406170.1
KAF8410265.1	tetracentron_sinense	KAF8410265.1
tetraena_mongolica_TmoA02G007930.1	tetraena_mongolica	tetraena_mongolica_TmoA02G007930.1
tetraena_mongolica_TmoA04G010650.1	tetraena_mongolica	tetraena_mongolica_TmoA04G010650.1
tetraena_mongolica_TmoA05G009770.1	tetraena_mongolica	tetraena_mongolica_TmoA05G009770.1
tetraena_mongolica_TmoA06G004910.1	tetraena_mongolica	tetraena_mongolica_TmoA06G004910.1
tetraena_mongolica_TmoB02G007720.1	tetraena_mongolica	tetraena_mongolica_TmoB02G007720.1
tetraena_mongolica_TmoB02G007730.1	tetraena_mongolica	tetraena_mongolica_TmoB02G007730.1
tetraena_mongolica_TmoB02G007740.1	tetraena_mongolica	tetraena_mongolica_TmoB02G007740.1
tetraena_mongolica_TmoB04G010880.1	tetraena_mongolica	tetraena_mongolica_TmoB04G010880.1
tetraena_mongolica_TmoB05G009070.1	tetraena_mongolica	tetraena_mongolica_TmoB05G009070.1
tetraena_mongolica_TmoB06G004780.1	tetraena_mongolica	tetraena_mongolica_TmoB06G004780.1
Tfil342400210440	tetralophozia_filiformis	Tfil342400210440
Tpelscaffold_40083890	tetraphis_pellucida	Tpelscaffold_40083890
Tpelscaffold_90231270	tetraphis_pellucida	Tpelscaffold_90231270
KAF5179681.1[Thalictrum	thalictrum_thalictroides	KAF5179681.1[Thalictrum
KAF5183108.1[Thalictrum	thalictrum_thalictroides	KAF5183108.1[Thalictrum
KAF5189424.1[Thalictrum	thalictrum_thalictroides	KAF5189424.1[Thalictrum
KAF5194751.1[Thalictrum	thalictrum_thalictroides	KAF5194751.1[Thalictrum
KAF5196604.1[Thalictrum	thalictrum_thalictroides	KAF5196604.1[Thalictrum
THsancontig_3720387050	thamnobryum_sandei	THsancontig_3720387050
THsancontig_980525400	thamnobryum_sandei	THsancontig_980525400
Tcac01G0007490.1	theobroma_cacao	Tcac01G0007490.1
Tcac01G0007490.2	theobroma_cacao	Tcac01G0007490.2
Tcac01G0007490.3	theobroma_cacao	Tcac01G0007490.3
Tcac01G0007490.4	theobroma_cacao	Tcac01G0007490.4
Tcac01G0012350.1	theobroma_cacao	Tcac01G0012350.1