SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Tcac01G0012420.1	theobroma_cacao	Tcac01G0012420.1
Tcac01G0012480.1	theobroma_cacao	Tcac01G0012480.1
Tcac02G0003290.1	theobroma_cacao	Tcac02G0003290.1
Tcac02G0003300.1	theobroma_cacao	Tcac02G0003300.1
Tcac02G0003310.1	theobroma_cacao	Tcac02G0003310.1
Tcac02G0003320.1	theobroma_cacao	Tcac02G0003320.1
Tcac04G0000990.1	theobroma_cacao	Tcac04G0000990.1
Tcac08G0007960.1	theobroma_cacao	Tcac08G0007960.1
thinopyrum_elongatum_GWHPABKY011257	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY011257
thinopyrum_elongatum_GWHPABKY011258	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY011258
thinopyrum_elongatum_GWHPABKY016172	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY016172
thinopyrum_elongatum_GWHPABKY020965	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY020965
thinopyrum_elongatum_GWHPABKY022785	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY022785
thinopyrum_elongatum_GWHPABKY023154	thinopyrum_elongatum	thinopyrum_elongatum_GWHPABKY023154
TarvThla_scaffold1550082490.1	thlaspi_arvense	TarvThla_scaffold1550082490.1
TarvThla_scaffold3280221460.1	thlaspi_arvense	TarvThla_scaffold3280221460.1
TarvThla_scaffold40254120.1	thlaspi_arvense	TarvThla_scaffold40254120.1
TarvThla_scaffold40254130.1	thlaspi_arvense	TarvThla_scaffold40254130.1
TarvThla_scaffold40254140.1	thlaspi_arvense	TarvThla_scaffold40254140.1
TarvThla_scaffold40254160.1	thlaspi_arvense	TarvThla_scaffold40254160.1
TarvThla_scaffold40254170.1	thlaspi_arvense	TarvThla_scaffold40254170.1
TarvThla_scaffold40254180.1	thlaspi_arvense	TarvThla_scaffold40254180.1
TarvThla_scaffold40254190.1	thlaspi_arvense	TarvThla_scaffold40254190.1
TarvThla_scaffold50282330.1	thlaspi_arvense	TarvThla_scaffold50282330.1
TarvThla_scaffold940382500.1	thlaspi_arvense	TarvThla_scaffold940382500.1
tiarella_polyphylla_GWHPBKAH007407	tiarella_polyphylla	tiarella_polyphylla_GWHPBKAH007407
tiarella_polyphylla_GWHPBKAH011938	tiarella_polyphylla	tiarella_polyphylla_GWHPBKAH011938
tiarella_polyphylla_GWHPBKAH013836	tiarella_polyphylla	tiarella_polyphylla_GWHPBKAH013836
tiarella_polyphylla_GWHPBKAH013969	tiarella_polyphylla	tiarella_polyphylla_GWHPBKAH013969
tiarella_polyphylla_GWHPBKAH013970	tiarella_polyphylla	tiarella_polyphylla_GWHPBKAH013970