SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
XP_038718240.1[Tripterygium	tripterygium_wilfordii	XP_038718240.1[Tripterygium
TraesCS2B02G487000.1	triticum_aestivum	TraesCS2B02G487000.1
TraesCS2B02G487100.1	triticum_aestivum	TraesCS2B02G487100.1
TraesCS2D02G465900.1	triticum_aestivum	TraesCS2D02G465900.1
TraesCS2D02G465900.2	triticum_aestivum	TraesCS2D02G465900.2
TraesCS3A02G243800.1.cds1	triticum_aestivum	TraesCS3A02G243800.1.cds1
TraesCS3B02G276400.1.cds1	triticum_aestivum	TraesCS3B02G276400.1.cds1
TraesCS4A02G037000.1	triticum_aestivum	TraesCS4A02G037000.1
TraesCS4A02G059900.1	triticum_aestivum	TraesCS4A02G059900.1
TraesCS4B02G235500.1	triticum_aestivum	TraesCS4B02G235500.1
TraesCS4B02G270100.1	triticum_aestivum	TraesCS4B02G270100.1
TraesCS4D02G099100.1	triticum_aestivum	TraesCS4D02G099100.1
TraesCS4D02G236900.1	triticum_aestivum	TraesCS4D02G236900.1
TraesCS4D02G269300.1	triticum_aestivum	TraesCS4D02G269300.1
triticum_monococcum_Tm.TA10622.r1.4AG0099420.1	triticum_monococcum	triticum_monococcum_Tm.TA10622.r1.4AG0099420.1
triticum_monococcum_Tm.TA10622.r1.4AG0108260.1	triticum_monococcum	triticum_monococcum_Tm.TA10622.r1.4AG0108260.1
triticum_monococcum_Tm.TA10622.r1.5AG0060130LC.1	triticum_monococcum	triticum_monococcum_Tm.TA10622.r1.5AG0060130LC.1
Ttur3AG0016460.1	triticum_turgidum	Ttur3AG0016460.1
Ttur3AG0016460.2	triticum_turgidum	Ttur3AG0016460.2
Ttur3AG0016460.3	triticum_turgidum	Ttur3AG0016460.3
Ttur3AG0022970.1	triticum_turgidum	Ttur3AG0022970.1
Ttur3AG0022970.2	triticum_turgidum	Ttur3AG0022970.2
Ttur3BG0026550.1	triticum_turgidum	Ttur3BG0026550.1
Ttur3BG0026550.2	triticum_turgidum	Ttur3BG0026550.2
Ttur4AG0003280.1	triticum_turgidum	Ttur4AG0003280.1
Ttur4AG0003280.2	triticum_turgidum	Ttur4AG0003280.2
Ttur4AG0003280.3	triticum_turgidum	Ttur4AG0003280.3
Ttur4AG0005980.1	triticum_turgidum	Ttur4AG0005980.1
Ttur4AG0005980.2	triticum_turgidum	Ttur4AG0005980.2
Ttur4AG0005980.3	triticum_turgidum	Ttur4AG0005980.3