SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
MCH97591.1[Trifolium	trifolium_medium	MCH97591.1[Trifolium
MCI01351.1[Trifolium	trifolium_medium	MCI01351.1[Trifolium
MCI07661.1[Trifolium	trifolium_medium	MCI07661.1[Trifolium
MCI24680.1[Trifolium	trifolium_medium	MCI24680.1[Trifolium
MCI27768.1[Trifolium	trifolium_medium	MCI27768.1[Trifolium
MCI40281.1[Trifolium	trifolium_medium	MCI40281.1[Trifolium
MCI43861.1[Trifolium	trifolium_medium	MCI43861.1[Trifolium
MCI62568.1[Trifolium	trifolium_medium	MCI62568.1[Trifolium
Tpra01G0020500.1	trifolium_pratense	Tpra01G0020500.1
Tpra02G0033000.1	trifolium_pratense	Tpra02G0033000.1
Tpra07G0019320.1	trifolium_pratense	Tpra07G0019320.1
Tpra07G0019340.1	trifolium_pratense	Tpra07G0019340.1
TpraFKJA01000268.10020690.1	trifolium_pratense	TpraFKJA01000268.10020690.1
TpraFKJA01000268.10020700.1	trifolium_pratense	TpraFKJA01000268.10020700.1
TpraFKJA01001186.10094450.1	trifolium_pratense	TpraFKJA01001186.10094450.1
TpraFKJA01004992.10123250.1	trifolium_pratense	TpraFKJA01004992.10123250.1
TpraFKJA01038177.10182880.1	trifolium_pratense	TpraFKJA01038177.10182880.1
trifolium_subterranum_Ts_v2.0_00490.1	trifolium_subterranum	trifolium_subterranum_Ts_v2.0_00490.1
trifolium_subterranum_Ts_v2.0_06766.1	trifolium_subterranum	trifolium_subterranum_Ts_v2.0_06766.1
trifolium_subterranum_Ts_v2.0_11843.1	trifolium_subterranum	trifolium_subterranum_Ts_v2.0_11843.1
trifolium_subterranum_Ts_v2.0_28254.1	trifolium_subterranum	trifolium_subterranum_Ts_v2.0_28254.1
trifolium_subterranum_Ts_v2.0_36407.1	trifolium_subterranum	trifolium_subterranum_Ts_v2.0_36407.1
XP_038680982.1[Tripterygium	tripterygium_wilfordii	XP_038680982.1[Tripterygium
XP_038680991.1[Tripterygium	tripterygium_wilfordii	XP_038680991.1[Tripterygium
XP_038680995.1[Tripterygium	tripterygium_wilfordii	XP_038680995.1[Tripterygium
XP_038681386.1[Tripterygium	tripterygium_wilfordii	XP_038681386.1[Tripterygium
XP_038682864.1[Tripterygium	tripterygium_wilfordii	XP_038682864.1[Tripterygium
XP_038683424.1[Tripterygium	tripterygium_wilfordii	XP_038683424.1[Tripterygium
XP_038686858.1[Tripterygium	tripterygium_wilfordii	XP_038686858.1[Tripterygium
XP_038716093.1[Tripterygium	tripterygium_wilfordii	XP_038716093.1[Tripterygium