PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
vitis_berlandieri_x_rupestris_VITVix110R_v1.0.hap_Vbe.chr18.ver1.0.g252580.p01 vitis_berlandieri_x_rupestris vitis_berlandieri_x_rupestris_VITVix110R_v1.0.hap_Vbe.chr18.ver1.0.g252580.p01
vitis_labrusca_maker-18-augustus-gene-68.34-mRNA-1 vitis_labrusca vitis_labrusca_maker-18-augustus-gene-68.34-mRNA-1
vitis_labrusca_maker-3-augustus-gene-123.31-mRNA-1 vitis_labrusca vitis_labrusca_maker-3-augustus-gene-123.31-mRNA-1
vitis_labrusca_maker-3-snap-gene-123.41-mRNA-1 vitis_labrusca vitis_labrusca_maker-3-snap-gene-123.41-mRNA-1
vitis_labrusca_maker-7-snap-gene-190.41-mRNA-1 vitis_labrusca vitis_labrusca_maker-7-snap-gene-190.41-mRNA-1
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr03.ver1.0.g040670.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr03.ver1.0.g040670.p01
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr03.ver1.0.g040680.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr03.ver1.0.g040680.p01
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr05.ver1.0.g068640.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr05.ver1.0.g068640.p01
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr07.ver1.0.g111540.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr07.ver1.0.g111540.p01
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr18.ver1.0.g307970.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr18.ver1.0.g307970.p01
vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr18.ver1.0.g307980.p01 vitis_rupestris_x_riparia vitis_rupestris_x_riparia_VITVix101-14Mgt_v1.0.hap_Vrp.chr18.ver1.0.g307980.p01
VIT_00s0441g00020.t01 vitis_vinifera VIT_00s0441g00020.t01
VIT_00s0525g00020.t01 vitis_vinifera VIT_00s0525g00020.t01
VIT_03s0088g01140.t01 vitis_vinifera VIT_03s0088g01140.t01
VIT_03s0088g01150.t01 vitis_vinifera VIT_03s0088g01150.t01
VIT_05s0020g04810.t01 vitis_vinifera VIT_05s0020g04810.t01
VIT_18s0001g08550.t01 vitis_vinifera VIT_18s0001g08550.t01
Vcarscaffold_120023560.1 volvox_carteri Vcarscaffold_120023560.1
warburgia_ugandensis_GWHPDQZE009257 warburgia_ugandensis warburgia_ugandensis_GWHPDQZE009257
warburgia_ugandensis_GWHPDQZE009637 warburgia_ugandensis warburgia_ugandensis_GWHPDQZE009637
warburgia_ugandensis_GWHPDQZE022379 warburgia_ugandensis warburgia_ugandensis_GWHPDQZE022379
Wmir02G0020390 welwitschia_mirabilis Wmir02G0020390
Wmir15G0000450 welwitschia_mirabilis Wmir15G0000450
wurfbainia_longiligularis_WL01Gene13474 wurfbainia_longiligularis wurfbainia_longiligularis_WL01Gene13474
wurfbainia_longiligularis_WL01Gene21122 wurfbainia_longiligularis wurfbainia_longiligularis_WL01Gene21122
wurfbainia_longiligularis_WL01Gene28267 wurfbainia_longiligularis wurfbainia_longiligularis_WL01Gene28267
wurfbainia_villosa_Wv_013507.m1 wurfbainia_villosa wurfbainia_villosa_Wv_013507.m1
wurfbainia_villosa_Wv_017232.m1 wurfbainia_villosa wurfbainia_villosa_Wv_017232.m1
wurfbainia_villosa_Wv_036928.m1 wurfbainia_villosa wurfbainia_villosa_Wv_036928.m1
wurfbainia_villosa_Wv_049135.m1 wurfbainia_villosa wurfbainia_villosa_Wv_049135.m1