PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Ctin05G0008360.1 carthamus_tinctorius Ctin05G0008360.1
Ctin07G0007810.1 carthamus_tinctorius Ctin07G0007810.1
Ctin08G0015060.1 carthamus_tinctorius Ctin08G0015060.1
Ctin09G0011700.1 carthamus_tinctorius Ctin09G0011700.1
Ctin10G0011420.1 carthamus_tinctorius Ctin10G0011420.1
Ctin10G0017140.1 carthamus_tinctorius Ctin10G0017140.1
Ctin10G0017140.2 carthamus_tinctorius Ctin10G0017140.2
Ctin10G0017140.3 carthamus_tinctorius Ctin10G0017140.3
Ctin10G0017140.4 carthamus_tinctorius Ctin10G0017140.4
Ctin10G0017140.5 carthamus_tinctorius Ctin10G0017140.5
Ccatscaffold158810036000 carya_cathayensis Ccatscaffold158810036000
Ccatscaffold222970103140 carya_cathayensis Ccatscaffold222970103140
Ccatscaffold222970103160 carya_cathayensis Ccatscaffold222970103160
Ccatscaffold240490120110 carya_cathayensis Ccatscaffold240490120110
Ccatscaffold316650181760 carya_cathayensis Ccatscaffold316650181760
Ccatscaffold390700224200 carya_cathayensis Ccatscaffold390700224200
Ccatscaffold434160244180 carya_cathayensis Ccatscaffold434160244180
Ccatscaffold612570292990 carya_cathayensis Ccatscaffold612570292990
Ccatscaffold666950301370 carya_cathayensis Ccatscaffold666950301370
carya_illinoinensis_Caril.02G024300.1.p carya_illinoinensis carya_illinoinensis_Caril.02G024300.1.p
carya_illinoinensis_Caril.03G068300.1.p carya_illinoinensis carya_illinoinensis_Caril.03G068300.1.p
carya_illinoinensis_Caril.05G025700.1.p carya_illinoinensis carya_illinoinensis_Caril.05G025700.1.p
carya_illinoinensis_Caril.07G035800.1.p carya_illinoinensis carya_illinoinensis_Caril.07G035800.1.p
carya_illinoinensis_Caril.07G168400.1.p carya_illinoinensis carya_illinoinensis_Caril.07G168400.1.p
carya_illinoinensis_Caril.08G054300.1.p carya_illinoinensis carya_illinoinensis_Caril.08G054300.1.p
carya_illinoinensis_Caril.08G147600.1.p carya_illinoinensis carya_illinoinensis_Caril.08G147600.1.p
carya_illinoinensis_Caril.08G147700.1.p carya_illinoinensis carya_illinoinensis_Caril.08G147700.1.p
carya_illinoinensis_Caril.08G147800.1.p carya_illinoinensis carya_illinoinensis_Caril.08G147800.1.p
carya_illinoinensis_Caril.08G147900.1.p carya_illinoinensis carya_illinoinensis_Caril.08G147900.1.p
castanea_dentata_Caden.02G172300.1.p castanea_dentata castanea_dentata_Caden.02G172300.1.p