PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Cglascaffold160052410 casuarina_glauca Cglascaffold160052410
Cglascaffold16080052610 casuarina_glauca Cglascaffold16080052610
Cglascaffold17600059890 casuarina_glauca Cglascaffold17600059890
Cglascaffold1810064860 casuarina_glauca Cglascaffold1810064860
Cglascaffold1810064870 casuarina_glauca Cglascaffold1810064870
Cglascaffold18300067180 casuarina_glauca Cglascaffold18300067180
Cglascaffold2280082140 casuarina_glauca Cglascaffold2280082140
Cglascaffold230084920 casuarina_glauca Cglascaffold230084920
Cglascaffold2450094780 casuarina_glauca Cglascaffold2450094780
Cglascaffold2450094790 casuarina_glauca Cglascaffold2450094790
Cglascaffold7640233280 casuarina_glauca Cglascaffold7640233280
Cglascaffold880249940 casuarina_glauca Cglascaffold880249940
Cnit2438760102280 catagonium_nitens Cnit2438760102280
Cnit2575050176930 catagonium_nitens Cnit2575050176930
catharanthus_roseus_CRO_T002088 catharanthus_roseus catharanthus_roseus_CRO_T002088
catharanthus_roseus_CRO_T002338 catharanthus_roseus catharanthus_roseus_CRO_T002338
catharanthus_roseus_CRO_T005754 catharanthus_roseus catharanthus_roseus_CRO_T005754
Clenscf_170029820.1 caulerpa_lentillifera Clenscf_170029820.1
CEame02G0044370 cenchrus_americanus CEame02G0044370
CEame05G0018600 cenchrus_americanus CEame05G0018600
CEame05G0036120 cenchrus_americanus CEame05G0036120
CEame07G0027090 cenchrus_americanus CEame07G0027090
cenchrus_fungigraminus_GWHPBWDX022488.1 cenchrus_fungigraminus cenchrus_fungigraminus_GWHPBWDX022488.1
cenchrus_fungigraminus_GWHPBWDX045444.1 cenchrus_fungigraminus cenchrus_fungigraminus_GWHPBWDX045444.1
cenchrus_fungigraminus_GWHPBWDX045445.1 cenchrus_fungigraminus cenchrus_fungigraminus_GWHPBWDX045445.1
cenchrus_fungigraminus_GWHPBWDX050057.1 cenchrus_fungigraminus cenchrus_fungigraminus_GWHPBWDX050057.1
cenchrus_fungigraminus_GWHPBWDX050058.1 cenchrus_fungigraminus cenchrus_fungigraminus_GWHPBWDX050058.1
PenpuA50059721.g cenchrus_purpureus PenpuA50059721.g
PenpuB50031084.g cenchrus_purpureus PenpuB50031084.g
centella_asiatica_evm.model.Scaffold_3.168 centella_asiatica centella_asiatica_evm.model.Scaffold_3.168