PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
centella_asiatica_evm.model.Scaffold_5.3125 centella_asiatica centella_asiatica_evm.model.Scaffold_5.3125
centella_asiatica_evm.model.Scaffold_6.1071 centella_asiatica centella_asiatica_evm.model.Scaffold_6.1071
centella_asiatica_evm.model.Scaffold_6.1072 centella_asiatica centella_asiatica_evm.model.Scaffold_6.1072
centella_asiatica_evm.model.Scaffold_6.627 centella_asiatica centella_asiatica_evm.model.Scaffold_6.627
centella_asiatica_evm.model.Scaffold_7.2751 centella_asiatica centella_asiatica_evm.model.Scaffold_7.2751
Cfolscaffold380211060 cephalotus_follicularis Cfolscaffold380211060
Cfolscaffold490254370 cephalotus_follicularis Cfolscaffold490254370
Cser01G0042440.1 cerasus_serrulata Cser01G0042440.1
Cser06G0023580.1 cerasus_serrulata Cser06G0023580.1
Cyed0A1G0029490 cerasus_yedoensis Cyed0A1G0029490
Cyed0A6G0029520 cerasus_yedoensis Cyed0A6G0029520
Cyed0A8G0020610 cerasus_yedoensis Cyed0A8G0020610
Cyed0A8G0020630 cerasus_yedoensis Cyed0A8G0020630
Cyed0E0G0095890 cerasus_yedoensis Cyed0E0G0095890
Cyed0E1G0034040 cerasus_yedoensis Cyed0E1G0034040
Cyed0E6G0017160 cerasus_yedoensis Cyed0E6G0017160
Cyed0E8G0024700 cerasus_yedoensis Cyed0E8G0024700
Cyed0E8G0024740 cerasus_yedoensis Cyed0E8G0024740
Cyed0E8G0024750 cerasus_yedoensis Cyed0E8G0024750
Ccanascaffold1|size26990920093280 cercis_canadensis Ccanascaffold1|size26990920093280
Ccanascaffold40|size10075840203510 cercis_canadensis Ccanascaffold40|size10075840203510
Ccanascaffold40|size10075840203520 cercis_canadensis Ccanascaffold40|size10075840203520
Ccanascaffold42|size9693710210700 cercis_canadensis Ccanascaffold42|size9693710210700
Ccanascaffold5|size23866360263780 cercis_canadensis Ccanascaffold5|size23866360263780
Ccanascaffold64|size7485710274090 cercis_canadensis Ccanascaffold64|size7485710274090
cercis_chinensis_GWHPBHAK008580 cercis_chinensis cercis_chinensis_GWHPBHAK008580
cercis_chinensis_GWHPBHAK016879 cercis_chinensis cercis_chinensis_GWHPBHAK016879
cercis_chinensis_GWHPBHAK023583 cercis_chinensis cercis_chinensis_GWHPBHAK023583
cercis_chinensis_GWHPBHAK027846 cercis_chinensis cercis_chinensis_GWHPBHAK027846
cercis_chinensis_GWHPBHAK027847 cercis_chinensis cercis_chinensis_GWHPBHAK027847