SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
actinidia_zhejiangensis_GWHPCBQB094153	actinidia_zhejiangensis	actinidia_zhejiangensis_GWHPCBQB094153
Acor01G0014130.1	aegiceras_corniculatum	Acor01G0014130.1
Acor13G0001490.1	aegiceras_corniculatum	Acor13G0001490.1
Acor20G0002070.1	aegiceras_corniculatum	Acor20G0002070.1
Atau2DG0050540.11	aegilops_tauschii	Atau2DG0050540.11
Atau2DG0050540.8	aegilops_tauschii	Atau2DG0050540.8
Atau3DG0027960.2	aegilops_tauschii	Atau3DG0027960.2
Atau4DG0011290.3	aegilops_tauschii	Atau4DG0011290.3
Atau4DG0028240.10	aegilops_tauschii	Atau4DG0028240.10
Atau4DG0028240.11	aegilops_tauschii	Atau4DG0028240.11
Atau4DG0028240.2	aegilops_tauschii	Atau4DG0028240.2
Atau4DG0028240.5	aegilops_tauschii	Atau4DG0028240.5
Atau4DG0028240.6	aegilops_tauschii	Atau4DG0028240.6
Atau4DG0028240.7	aegilops_tauschii	Atau4DG0028240.7
Atau4DG0028240.8	aegilops_tauschii	Atau4DG0028240.8
Atau4DG0028240.9	aegilops_tauschii	Atau4DG0028240.9
Atau4DG0031690.1	aegilops_tauschii	Atau4DG0031690.1
Atau4DG0031690.2	aegilops_tauschii	Atau4DG0031690.2
Atau4DG0031690.3	aegilops_tauschii	Atau4DG0031690.3
Atau5DG0043480.3	aegilops_tauschii	Atau5DG0043480.3
Al_clc_g5550	aeluropus_littoralis	Al_clc_g5550
Asubscaffold_130131270	aerobryopsis_subdivergens	Asubscaffold_130131270
Asubscaffold_140140790	aerobryopsis_subdivergens	Asubscaffold_140140790
Asubscaffold_90281420	aerobryopsis_subdivergens	Asubscaffold_90281420
Aeve03G0021020.1	aeschynomene_evenia	Aeve03G0021020.1
Aeve04G0007240.1	aeschynomene_evenia	Aeve04G0007240.1
Aeve04G0013980.1	aeschynomene_evenia	Aeve04G0013980.1
Aeve07G0009430.1	aeschynomene_evenia	Aeve07G0009430.1
Aeve08G0004350.1	aeschynomene_evenia	Aeve08G0004350.1
AaraAA_C1585670031320	aethionema_arabicum	AaraAA_C1585670031320