SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
AaraAA_scaffold16540089360	aethionema_arabicum	AaraAA_scaffold16540089360
AaraAA_scaffold34280176370	aethionema_arabicum	AaraAA_scaffold34280176370
AaraAA_scaffold34830178440	aethionema_arabicum	AaraAA_scaffold34830178440
AaraAA_scaffold36760191530	aethionema_arabicum	AaraAA_scaffold36760191530
AaraAA_scaffold36760191540	aethionema_arabicum	AaraAA_scaffold36760191540
AaraAA_scaffold50570254460	aethionema_arabicum	AaraAA_scaffold50570254460
AaraAA_scaffold58290306580	aethionema_arabicum	AaraAA_scaffold58290306580
GWHPBISH013675	akebia_trifoliata	GWHPBISH013675
GWHPBISH016625	akebia_trifoliata	GWHPBISH016625
Avestig00000001_pilon0004570.1	aldrovanda_vesiculosa	Avestig00000001_pilon0004570.1
Avestig00002141_pilon0168420.1	aldrovanda_vesiculosa	Avestig00002141_pilon0168420.1
Agluscaffold424463_cov1080247570	alnus_glutinosa	Agluscaffold424463_cov1080247570
Agluscaffold5243_cov1030318260	alnus_glutinosa	Agluscaffold5243_cov1030318260
Agluscaffold6101_cov1030347090	alnus_glutinosa	Agluscaffold6101_cov1030347090
alnus_rubra_ALNRU00005972-RA	alnus_rubra	alnus_rubra_ALNRU00005972-RA
alnus_rubra_ALNRU00011927-RA	alnus_rubra	alnus_rubra_ALNRU00011927-RA
alnus_rubra_ALNRU00046739-RA	alnus_rubra	alnus_rubra_ALNRU00046739-RA
alnus_rubra_ALNRU00048437-RA	alnus_rubra	alnus_rubra_ALNRU00048437-RA
alnus_rubra_ALNRU00109199-RA	alnus_rubra	alnus_rubra_ALNRU00109199-RA
alnus_rubra_ALNRU00127750-RA	alnus_rubra	alnus_rubra_ALNRU00127750-RA
alstonia_scholaris_tjs02571	alstonia_scholaris	alstonia_scholaris_tjs02571
alstonia_scholaris_tjs03885	alstonia_scholaris	alstonia_scholaris_tjs03885
alstonia_scholaris_tjs13383	alstonia_scholaris	alstonia_scholaris_tjs13383
alstonia_scholaris_tjs13573	alstonia_scholaris	alstonia_scholaris_tjs13573
alstonia_scholaris_tjs15887	alstonia_scholaris	alstonia_scholaris_tjs15887
alstonia_scholaris_tjs22374	alstonia_scholaris	alstonia_scholaris_tjs22374
alstonia_scholaris_tjs22375	alstonia_scholaris	alstonia_scholaris_tjs22375
alstonia_scholaris_tjs25281	alstonia_scholaris	alstonia_scholaris_tjs25281
alstonia_scholaris_tjs31095	alstonia_scholaris	alstonia_scholaris_tjs31095
alstonia_scholaris_tjs31131	alstonia_scholaris	alstonia_scholaris_tjs31131