PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
CLchi24G0002920.1 cladopus_chinensis CLchi24G0002920.1
CsonA4G0028980.1 cleistogenes_songorica CsonA4G0028980.1
CsonB4G0027370.1 cleistogenes_songorica CsonB4G0027370.1
CsonB7G0015300.1 cleistogenes_songorica CsonB7G0015300.1
Carb1920023830.1 clethra_arborea Carb1920023830.1
Carb969730182020.1 clethra_arborea Carb969730182020.1
Carb969730182040.1 clethra_arborea Carb969730182040.1
Carb985350270490.1 clethra_arborea Carb985350270490.1
Carb989160293990.1 clethra_arborea Carb989160293990.1
CLame636630018420 climacium_americanum CLame636630018420
CLame667730197690 climacium_americanum CLame667730197690
CLame668920230870 climacium_americanum CLame668920230870
Cnucscaffold34680153140 cocos_nucifera Cnucscaffold34680153140
Cnucscaffold47660193010 cocos_nucifera Cnucscaffold47660193010
Cnucscaffold57950216810 cocos_nucifera Cnucscaffold57950216810
codonopsis_lanceolata_Cl_chr02_19690T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr02_19690T
codonopsis_lanceolata_Cl_chr02_19700T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr02_19700T
codonopsis_lanceolata_Cl_chr03_23720T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr03_23720T
codonopsis_lanceolata_Cl_chr03_23730T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr03_23730T
codonopsis_lanceolata_Cl_chr04_00090T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr04_00090T
codonopsis_lanceolata_Cl_chr04_00100T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr04_00100T
codonopsis_lanceolata_Cl_chr05_14380T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr05_14380T
codonopsis_lanceolata_Cl_chr05_28360T codonopsis_lanceolata codonopsis_lanceolata_Cl_chr05_28360T
Ccane01G0000530.1 coffea_canephora Ccane01G0000530.1
Ccane02G0020360.1 coffea_canephora Ccane02G0020360.1
Ccane07G0007420.1 coffea_canephora Ccane07G0007420.1
Ccane08G0011580.1 coffea_canephora Ccane08G0011580.1
Ccane10G0004050.1 coffea_canephora Ccane10G0004050.1
Ccane10G0007750.1 coffea_canephora Ccane10G0007750.1
coix_lacryma-jobi_GWHPAAYR014030 coix_lacryma_jobi coix_lacryma-jobi_GWHPAAYR014030