SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
DlotDlo_pri0241F.10361790.1	diospyros_lotus	DlotDlo_pri0241F.10361790.1
DlotDlo_pri0365F.10405440.1	diospyros_lotus	DlotDlo_pri0365F.10405440.1
Dole04G0006940.1	diospyros_oleifera	Dole04G0006940.1
Dole05G0011690.1	diospyros_oleifera	Dole05G0011690.1
Dole14G0001310.1	diospyros_oleifera	Dole14G0001310.1
Dole14G0015890.1	diospyros_oleifera	Dole14G0015890.1
Dole15G0009750.1	diospyros_oleifera	Dole15G0009750.1
DIPfulscaffold_30055650	diphyscium_fulvifolium	DIPfulscaffold_30055650
Dcolcontig_310144280	distichophyllum_collenchymatosom	Dcolcontig_310144280
Dcolcontig_890202570	distichophyllum_collenchymatosom	Dcolcontig_890202570
Dcolcontig_960226890	distichophyllum_collenchymatosom	Dcolcontig_960226890
Dcolcontig_310144280	distichophyllum_collenchymatosum	Dcolcontig_310144280
Dcolcontig_890202570	distichophyllum_collenchymatosum	Dcolcontig_890202570
Dcolcontig_960226890	distichophyllum_collenchymatosum	Dcolcontig_960226890
dorcoceras_hygrometricum_KZV29906.1	dorcoceras_hygrometricum	dorcoceras_hygrometricum_KZV29906.1
dorcoceras_hygrometricum_KZV30171.1	dorcoceras_hygrometricum	dorcoceras_hygrometricum_KZV30171.1
dorcoceras_hygrometricum_KZV50022.1	dorcoceras_hygrometricum	dorcoceras_hygrometricum_KZV50022.1
dorcoceras_hygrometricum_KZV53283.1	dorcoceras_hygrometricum	dorcoceras_hygrometricum_KZV53283.1
dorcoceras_hygrometricum_KZV54514.1	dorcoceras_hygrometricum	dorcoceras_hygrometricum_KZV54514.1
Ddruscaffold1460027120	dryas_drummondii	Ddruscaffold1460027120
Ddruscaffold1460030420	dryas_drummondii	Ddruscaffold1460030420
Ddruscaffold3030126000	dryas_drummondii	Ddruscaffold3030126000
Ddruscaffold3800151600	dryas_drummondii	Ddruscaffold3800151600
Ddruscaffold3800151610	dryas_drummondii	Ddruscaffold3800151610
Dsalscaffold2770067650.1	dunaliella_salina	Dsalscaffold2770067650.1
XP_022722433.1	durio_zibethinus	XP_022722433.1
XP_022724947.1	durio_zibethinus	XP_022724947.1
XP_022726939.1	durio_zibethinus	XP_022726939.1
XP_022740800.1	durio_zibethinus	XP_022740800.1
XP_022740801.1	durio_zibethinus	XP_022740801.1