PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
XP_022740802.1 durio_zibethinus XP_022740802.1
XP_022740803.1 durio_zibethinus XP_022740803.1
XP_022748622.1 durio_zibethinus XP_022748622.1
XP_022749233.1 durio_zibethinus XP_022749233.1
XP_022752059.1 durio_zibethinus XP_022752059.1
XP_022762836.1 durio_zibethinus XP_022762836.1
XP_022768599.1 durio_zibethinus XP_022768599.1
XP_022772253.1 durio_zibethinus XP_022772253.1
echinochloa_oryzicola_GWHPBDNS004606 echinochloa_oryzicola echinochloa_oryzicola_GWHPBDNS004606
echinochloa_oryzicola_GWHPBDNS037798 echinochloa_oryzicola echinochloa_oryzicola_GWHPBDNS037798
Eobt5942120072060 ectropothecium_obtusulum Eobt5942120072060
Eobt5945710215770 ectropothecium_obtusulum Eobt5945710215770
elaeis_guineensis_Egu003943-mRNA-1 elaeis_guineensis elaeis_guineensis_Egu003943-mRNA-1
elaeis_guineensis_Egu004143-mRNA-1 elaeis_guineensis elaeis_guineensis_Egu004143-mRNA-1
elaeis_guineensis_Egu010266-mRNA-1 elaeis_guineensis elaeis_guineensis_Egu010266-mRNA-1
elaeis_guineensis_Egu010267-mRNA-1 elaeis_guineensis elaeis_guineensis_Egu010267-mRNA-1
elaeis_guineensis_Egu024212-mRNA-1 elaeis_guineensis elaeis_guineensis_Egu024212-mRNA-1
Ecor3AG0022740.1 eleusine_coracana Ecor3AG0022740.1
Ecor3BG0025260.1 eleusine_coracana Ecor3BG0025260.1
engelhardia_roxburghiana_AroxChr02G000753.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr02G000753.1
engelhardia_roxburghiana_AroxChr02G002093.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr02G002093.1
engelhardia_roxburghiana_AroxChr02G002094.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr02G002094.1
engelhardia_roxburghiana_AroxChr03G002333.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr03G002333.1
engelhardia_roxburghiana_AroxChr05G000235.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr05G000235.1
engelhardia_roxburghiana_AroxChr12G000522.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr12G000522.1
engelhardia_roxburghiana_AroxChr12G001506.1 engelhardia_roxburghiana engelhardia_roxburghiana_AroxChr12G001506.1
Ecur05G0034490.1 eragrostis_curvula Ecur05G0034490.1
Ecur05G0039770.1 eragrostis_curvula Ecur05G0039770.1
Ecur07G0009240.1 eragrostis_curvula Ecur07G0009240.1
En_0022352.mRNA1 eragrostis_nindensis En_0022352.mRNA1