SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
GbarD05G0021620	gossypium_barbadense	GbarD05G0021620
GbarD06G0002520	gossypium_barbadense	GbarD06G0002520
GbarD11G0021970	gossypium_barbadense	GbarD11G0021970
Gbarscaffold4874_obj0005770	gossypium_barbadense	Gbarscaffold4874_obj0005770
Gbarscaffold7085_obj0007120	gossypium_barbadense	Gbarscaffold7085_obj0007120
gossypium_bickii_Gbic_01G017850.1	gossypium_bickii	gossypium_bickii_Gbic_01G017850.1
gossypium_bickii_Gbic_02G018550.1	gossypium_bickii	gossypium_bickii_Gbic_02G018550.1
gossypium_bickii_Gbic_03G029150.1	gossypium_bickii	gossypium_bickii_Gbic_03G029150.1
gossypium_bickii_Gbic_04G021450.1	gossypium_bickii	gossypium_bickii_Gbic_04G021450.1
gossypium_bickii_Gbic_04G021460.1	gossypium_bickii	gossypium_bickii_Gbic_04G021460.1
gossypium_bickii_Gbic_04G021480.1	gossypium_bickii	gossypium_bickii_Gbic_04G021480.1
gossypium_bickii_Gbic_04G021500.1	gossypium_bickii	gossypium_bickii_Gbic_04G021500.1
gossypium_bickii_Gbic_04G021510.1	gossypium_bickii	gossypium_bickii_Gbic_04G021510.1
gossypium_bickii_Gbic_04G021520.1	gossypium_bickii	gossypium_bickii_Gbic_04G021520.1
gossypium_bickii_Gbic_04G021530.1	gossypium_bickii	gossypium_bickii_Gbic_04G021530.1
gossypium_bickii_Gbic_04G021540.1	gossypium_bickii	gossypium_bickii_Gbic_04G021540.1
gossypium_bickii_Gbic_04G021550.1	gossypium_bickii	gossypium_bickii_Gbic_04G021550.1
gossypium_bickii_Gbic_04G021560.1	gossypium_bickii	gossypium_bickii_Gbic_04G021560.1
gossypium_bickii_Gbic_05G021980.1	gossypium_bickii	gossypium_bickii_Gbic_05G021980.1
gossypium_bickii_Gbic_06G024860.1	gossypium_bickii	gossypium_bickii_Gbic_06G024860.1
gossypium_bickii_Gbic_11G024060.1	gossypium_bickii	gossypium_bickii_Gbic_11G024060.1
Gher01G0014030.1	gossypium_herbaceum	Gher01G0014030.1
Gher02G0019310.1	gossypium_herbaceum	Gher02G0019310.1
Gher03G0000720.1	gossypium_herbaceum	Gher03G0000720.1
Gher04G0022480.1	gossypium_herbaceum	Gher04G0022480.1
Gher04G0022490.1	gossypium_herbaceum	Gher04G0022490.1
Gher04G0022500.1	gossypium_herbaceum	Gher04G0022500.1
Gher04G0022510.1	gossypium_herbaceum	Gher04G0022510.1
Gher04G0022520.1	gossypium_herbaceum	Gher04G0022520.1
Gher04G0022530.1	gossypium_herbaceum	Gher04G0022530.1