SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
GhirD04G0020750.2	gossypium_hirsutum	GhirD04G0020750.2
GhirD04G0020760.1	gossypium_hirsutum	GhirD04G0020760.1
GhirD04G0020770.1	gossypium_hirsutum	GhirD04G0020770.1
GhirD04G0020780.1	gossypium_hirsutum	GhirD04G0020780.1
GhirD04G0020790.1	gossypium_hirsutum	GhirD04G0020790.1
GhirD04G0020800.1	gossypium_hirsutum	GhirD04G0020800.1
GhirD04G0020800.2	gossypium_hirsutum	GhirD04G0020800.2
GhirD05G0023270.1	gossypium_hirsutum	GhirD05G0023270.1
GhirD06G0002760.1	gossypium_hirsutum	GhirD06G0002760.1
GhirD07G0001410.1	gossypium_hirsutum	GhirD07G0001410.1
GhirD07G0001410.2	gossypium_hirsutum	GhirD07G0001410.2
GhirD07G0001410.3	gossypium_hirsutum	GhirD07G0001410.3
GhirD11G0023350.1	gossypium_hirsutum	GhirD11G0023350.1
gossypium_longicalyx_Glon_01G005720.1	gossypium_longicalyx	gossypium_longicalyx_Glon_01G005720.1
gossypium_longicalyx_Glon_01G015060.1	gossypium_longicalyx	gossypium_longicalyx_Glon_01G015060.1
gossypium_longicalyx_Glon_02G021360.1	gossypium_longicalyx	gossypium_longicalyx_Glon_02G021360.1
gossypium_longicalyx_Glon_03G029450.1	gossypium_longicalyx	gossypium_longicalyx_Glon_03G029450.1
gossypium_longicalyx_Glon_04G002130.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002130.1
gossypium_longicalyx_Glon_04G002150.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002150.1
gossypium_longicalyx_Glon_04G002160.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002160.1
gossypium_longicalyx_Glon_04G002170.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002170.1
gossypium_longicalyx_Glon_04G002180.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002180.1
gossypium_longicalyx_Glon_04G002190.1	gossypium_longicalyx	gossypium_longicalyx_Glon_04G002190.1
gossypium_longicalyx_Glon_06G002830.1	gossypium_longicalyx	gossypium_longicalyx_Glon_06G002830.1
gossypium_longicalyx_Glon_09G003050.1	gossypium_longicalyx	gossypium_longicalyx_Glon_09G003050.1
gossypium_longicalyx_Glon_11G023340.1	gossypium_longicalyx	gossypium_longicalyx_Glon_11G023340.1
GmusA01G0012960.1	gossypium_mustelinum	GmusA01G0012960.1
GmusA02G0016770.1	gossypium_mustelinum	GmusA02G0016770.1
GmusA03G0023380.1	gossypium_mustelinum	GmusA03G0023380.1
GmusA04G0016420.1	gossypium_mustelinum	GmusA04G0016420.1