PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Grai12G0016300.5 gossypium_raimondii Grai12G0016300.5
Graiscaffold_2150001400.1 gossypium_raimondii Graiscaffold_2150001400.1
Graiscaffold_2150001410.1 gossypium_raimondii Graiscaffold_2150001410.1
Graiscaffold_2150001410.2 gossypium_raimondii Graiscaffold_2150001410.2
Graiscaffold_2150001410.3 gossypium_raimondii Graiscaffold_2150001410.3
Graiscaffold_2150001410.4 gossypium_raimondii Graiscaffold_2150001410.4
gossypium_rotundifolium_Grot_01G005750.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_01G005750.1
gossypium_rotundifolium_Grot_02G017850.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_02G017850.1
gossypium_rotundifolium_Grot_03G000660.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_03G000660.1
gossypium_rotundifolium_Grot_04G022530.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_04G022530.1
gossypium_rotundifolium_Grot_04G022540.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_04G022540.1
gossypium_rotundifolium_Grot_04G022550.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_04G022550.1
gossypium_rotundifolium_Grot_04G022560.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_04G022560.1
gossypium_rotundifolium_Grot_04G022570.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_04G022570.1
gossypium_rotundifolium_Grot_05G020510.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_05G020510.1
gossypium_rotundifolium_Grot_06G024990.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_06G024990.1
gossypium_rotundifolium_Grot_11G016170.1 gossypium_rotundifolium gossypium_rotundifolium_Grot_11G016170.1
gossypium_stocksii_Gsto_01G013660.1 gossypium_stocksii gossypium_stocksii_Gsto_01G013660.1
gossypium_stocksii_Gsto_01G022240.1 gossypium_stocksii gossypium_stocksii_Gsto_01G022240.1
gossypium_stocksii_Gsto_02G003330.2 gossypium_stocksii gossypium_stocksii_Gsto_02G003330.2
gossypium_stocksii_Gsto_03G028810.1 gossypium_stocksii gossypium_stocksii_Gsto_03G028810.1
gossypium_stocksii_Gsto_04G002400.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002400.1
gossypium_stocksii_Gsto_04G002410.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002410.1
gossypium_stocksii_Gsto_04G002420.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002420.1
gossypium_stocksii_Gsto_04G002430.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002430.1
gossypium_stocksii_Gsto_04G002440.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002440.1
gossypium_stocksii_Gsto_04G002470.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002470.1
gossypium_stocksii_Gsto_04G002490.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002490.1
gossypium_stocksii_Gsto_04G002510.1 gossypium_stocksii gossypium_stocksii_Gsto_04G002510.1
gossypium_stocksii_Gsto_04G018690.2 gossypium_stocksii gossypium_stocksii_Gsto_04G018690.2