PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
gossypium_stocksii_Gsto_05G023260.1 gossypium_stocksii gossypium_stocksii_Gsto_05G023260.1
gossypium_stocksii_Gsto_06G003010.1 gossypium_stocksii gossypium_stocksii_Gsto_06G003010.1
gossypium_stocksii_Gsto_11G022890.1 gossypium_stocksii gossypium_stocksii_Gsto_11G022890.1
gossypium_sturtianum_Gstu01G005930 gossypium_sturtianum gossypium_sturtianum_Gstu01G005930
gossypium_sturtianum_Gstu01G014950 gossypium_sturtianum gossypium_sturtianum_Gstu01G014950
gossypium_sturtianum_Gstu02G019450 gossypium_sturtianum gossypium_sturtianum_Gstu02G019450
gossypium_sturtianum_Gstu03G000660 gossypium_sturtianum gossypium_sturtianum_Gstu03G000660
gossypium_sturtianum_Gstu04G002030 gossypium_sturtianum gossypium_sturtianum_Gstu04G002030
gossypium_sturtianum_Gstu04G002040 gossypium_sturtianum gossypium_sturtianum_Gstu04G002040
gossypium_sturtianum_Gstu04G002050 gossypium_sturtianum gossypium_sturtianum_Gstu04G002050
gossypium_sturtianum_Gstu04G002060 gossypium_sturtianum gossypium_sturtianum_Gstu04G002060
gossypium_sturtianum_Gstu04G002070 gossypium_sturtianum gossypium_sturtianum_Gstu04G002070
gossypium_sturtianum_Gstu04G002090 gossypium_sturtianum gossypium_sturtianum_Gstu04G002090
gossypium_sturtianum_Gstu04G002110 gossypium_sturtianum gossypium_sturtianum_Gstu04G002110
gossypium_sturtianum_Gstu04G002120 gossypium_sturtianum gossypium_sturtianum_Gstu04G002120
gossypium_sturtianum_Gstu05G003980 gossypium_sturtianum gossypium_sturtianum_Gstu05G003980
gossypium_sturtianum_Gstu06G025980 gossypium_sturtianum gossypium_sturtianum_Gstu06G025980
gossypium_sturtianum_Gstu11G024140 gossypium_sturtianum gossypium_sturtianum_Gstu11G024140
GtomA01G0014630.1 gossypium_tomentosum GtomA01G0014630.1
GtomA01G0014630.2 gossypium_tomentosum GtomA01G0014630.2
GtomA01G0014630.3 gossypium_tomentosum GtomA01G0014630.3
GtomA02G0018170.1 gossypium_tomentosum GtomA02G0018170.1
GtomA03G0025100.1 gossypium_tomentosum GtomA03G0025100.1
GtomA04G0017090.1 gossypium_tomentosum GtomA04G0017090.1
GtomA04G0017100.1 gossypium_tomentosum GtomA04G0017100.1
GtomA04G0017110.1 gossypium_tomentosum GtomA04G0017110.1
GtomA04G0017130.1 gossypium_tomentosum GtomA04G0017130.1
GtomA04G0017150.1 gossypium_tomentosum GtomA04G0017150.1
GtomA04G0017150.2 gossypium_tomentosum GtomA04G0017150.2
GtomA04G0017160.1 gossypium_tomentosum GtomA04G0017160.1