PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
GtomA05G0023020.1 gossypium_tomentosum GtomA05G0023020.1
GtomA06G0002970.1 gossypium_tomentosum GtomA06G0002970.1
GtomA07G0001300.1 gossypium_tomentosum GtomA07G0001300.1
GtomA11G0023980.1 gossypium_tomentosum GtomA11G0023980.1
GtomD01G0014660.1 gossypium_tomentosum GtomD01G0014660.1
GtomD02G0028930.1 gossypium_tomentosum GtomD02G0028930.1
GtomD02G0028930.2 gossypium_tomentosum GtomD02G0028930.2
GtomD02G0028930.3 gossypium_tomentosum GtomD02G0028930.3
GtomD03G0003460.1 gossypium_tomentosum GtomD03G0003460.1
GtomD04G0021100.1 gossypium_tomentosum GtomD04G0021100.1
GtomD04G0021110.1 gossypium_tomentosum GtomD04G0021110.1
GtomD04G0021120.1 gossypium_tomentosum GtomD04G0021120.1
GtomD04G0021130.1 gossypium_tomentosum GtomD04G0021130.1
GtomD04G0021150.1 gossypium_tomentosum GtomD04G0021150.1
GtomD04G0021160.1 gossypium_tomentosum GtomD04G0021160.1
GtomD04G0021170.1 gossypium_tomentosum GtomD04G0021170.1
GtomD04G0021180.1 gossypium_tomentosum GtomD04G0021180.1
GtomD05G0023420.1 gossypium_tomentosum GtomD05G0023420.1
GtomD06G0003180.1 gossypium_tomentosum GtomD06G0003180.1
GtomD06G0003180.2 gossypium_tomentosum GtomD06G0003180.2
GtomD11G0023540.1 gossypium_tomentosum GtomD11G0023540.1
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.01g014660.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.01g014660.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.01g318460.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.01g318460.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.02g031990.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.02g031990.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.03g051290.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.03g051290.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101460.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101460.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101470.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101470.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101480.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101480.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101490.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101490.m01.polypeptide
Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101500.m01.polypeptide gossypium_turneri Gossypium-turneri-TURN-v1.0.a2-publish_TURN.04g101500.m01.polypeptide