PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Amac1581040053170 andreaeobryum_macrosporum Amac1581040053170
Amac791410134460 andreaeobryum_macrosporum Amac791410134460
andrographis_paniculata_XP_051124318.1 andrographis_paniculata andrographis_paniculata_XP_051124318.1
andrographis_paniculata_XP_051132628.1 andrographis_paniculata andrographis_paniculata_XP_051132628.1
andrographis_paniculata_XP_051132629.1 andrographis_paniculata andrographis_paniculata_XP_051132629.1
andrographis_paniculata_XP_051132630.1 andrographis_paniculata andrographis_paniculata_XP_051132630.1
andrographis_paniculata_XP_051132631.1 andrographis_paniculata andrographis_paniculata_XP_051132631.1
andrographis_paniculata_XP_051136359.1 andrographis_paniculata andrographis_paniculata_XP_051136359.1
andrographis_paniculata_XP_051137593.1 andrographis_paniculata andrographis_paniculata_XP_051137593.1
andrographis_paniculata_XP_051144271.1 andrographis_paniculata andrographis_paniculata_XP_051144271.1
andrographis_paniculata_XP_051146949.1 andrographis_paniculata andrographis_paniculata_XP_051146949.1
andrographis_paniculata_XP_051148660.1 andrographis_paniculata andrographis_paniculata_XP_051148660.1
andrographis_paniculata_XP_051149031.1 andrographis_paniculata andrographis_paniculata_XP_051149031.1
andrographis_paniculata_XP_051149155.1 andrographis_paniculata andrographis_paniculata_XP_051149155.1
angelica_sinensis_AS02G03715-RA angelica_sinensis angelica_sinensis_AS02G03715-RA
angelica_sinensis_AS03G00240-RA angelica_sinensis angelica_sinensis_AS03G00240-RA
angelica_sinensis_AS03G02543-RA angelica_sinensis angelica_sinensis_AS03G02543-RA
angelica_sinensis_AS04G00780-RA angelica_sinensis angelica_sinensis_AS04G00780-RA
angelica_sinensis_AS05G00124-RA angelica_sinensis angelica_sinensis_AS05G00124-RA
angelica_sinensis_AS10G02063-RA angelica_sinensis angelica_sinensis_AS10G02063-RA
angelica_sinensis_AS10G02591-RA angelica_sinensis angelica_sinensis_AS10G02591-RA
anisodus_acutangulus_KAJ8537830.1 anisodus_acutangulus anisodus_acutangulus_KAJ8537830.1
anisodus_acutangulus_KAJ8541222.1 anisodus_acutangulus anisodus_acutangulus_KAJ8541222.1
anisodus_acutangulus_KAJ8544850.1 anisodus_acutangulus anisodus_acutangulus_KAJ8544850.1
anisodus_acutangulus_KAJ8555333.1 anisodus_acutangulus anisodus_acutangulus_KAJ8555333.1
anisodus_acutangulus_KAJ8557939.1 anisodus_acutangulus anisodus_acutangulus_KAJ8557939.1
annona_cherimola_Anche102Chr4g0049260.1 annona_cherimola annona_cherimola_Anche102Chr4g0049260.1
annona_cherimola_Anche102Chr4g0049540.1 annona_cherimola annona_cherimola_Anche102Chr4g0049540.1
annona_cherimola_Anche102Chr6g0091360.1 annona_cherimola annona_cherimola_Anche102Chr6g0091360.1
annona_cherimola_Anche102Chr6g0091580.1 annona_cherimola annona_cherimola_Anche102Chr6g0091580.1