PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
amaranthus_tricolor_g1566.t1 amaranthus_tricolor amaranthus_tricolor_g1566.t1
amaranthus_tricolor_g18633.t1 amaranthus_tricolor amaranthus_tricolor_g18633.t1
At.01g047060-v1.1.a1 amaranthus_tuberculatus At.01g047060-v1.1.a1
At.02g065120-v1.1.a1 amaranthus_tuberculatus At.02g065120-v1.1.a1
At.03g167390-v1.1.a1 amaranthus_tuberculatus At.03g167390-v1.1.a1
AtriAmTr_v1.0_scaffold000020007850.1 amborella_trichopoda AtriAmTr_v1.0_scaffold000020007850.1
AtriAmTr_v1.0_scaffold000650162290.1 amborella_trichopoda AtriAmTr_v1.0_scaffold000650162290.1
AnanContig000450033400.1 ammopiptanthus_nanus AnanContig000450033400.1
AnanContig001000073770.1 ammopiptanthus_nanus AnanContig001000073770.1
AnanContig001450106910.1 ammopiptanthus_nanus AnanContig001450106910.1
AnanContig001450106920.1 ammopiptanthus_nanus AnanContig001450106920.1
AnanContig001900133310.1 ammopiptanthus_nanus AnanContig001900133310.1
AnanContig005730279040.1 ammopiptanthus_nanus AnanContig005730279040.1
AnanContig010100315850.1 ammopiptanthus_nanus AnanContig010100315850.1
AedgHiC_scaffold_100053770 amphicarpaea_edgeworthii AedgHiC_scaffold_100053770
AedgHiC_scaffold_40145630 amphicarpaea_edgeworthii AedgHiC_scaffold_40145630
AedgHiC_scaffold_40149060 amphicarpaea_edgeworthii AedgHiC_scaffold_40149060
AedgHiC_scaffold_40155730 amphicarpaea_edgeworthii AedgHiC_scaffold_40155730
AedgHiC_scaffold_60186740 amphicarpaea_edgeworthii AedgHiC_scaffold_60186740
Abra16G0009470.1 ananas_bracteatus Abra16G0009470.1
Acom15G0008590.1 ananas_comosus Acom15G0008590.1
Arupctg000944_np121212120090660 andreaea_rupestris Arupctg000944_np121212120090660
Arupctg001004_np121212120099020 andreaea_rupestris Arupctg001004_np121212120099020
Arupctg001820_np121212120223690 andreaea_rupestris Arupctg001820_np121212120223690
Arupctg001820_np121212120223830 andreaea_rupestris Arupctg001820_np121212120223830
Awil11890019780 andreaea_wilsonii Awil11890019780
Awil380106710 andreaea_wilsonii Awil380106710
Awil570125000 andreaea_wilsonii Awil570125000
Awil7400134300 andreaea_wilsonii Awil7400134300
Amac1462800029480 andreaeobryum_macrosporum Amac1462800029480