SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Itril01G0001120.2	ipomoea_triloba	Itril01G0001120.2
Itril01G0025890.1	ipomoea_triloba	Itril01G0025890.1
Itril09G0002820.1	ipomoea_triloba	Itril09G0002820.1
Itril09G0002820.2	ipomoea_triloba	Itril09G0002820.2
Itril12G0004280.1	ipomoea_triloba	Itril12G0004280.1
Itril15G0015500.1	ipomoea_triloba	Itril15G0015500.1
Iind00G0008190.1	isatis_indigotica	Iind00G0008190.1
Iind00G0008200.1	isatis_indigotica	Iind00G0008200.1
Iind00G0008200.2	isatis_indigotica	Iind00G0008200.2
Iind00G0008210.1	isatis_indigotica	Iind00G0008210.1
Iind00G0008210.2	isatis_indigotica	Iind00G0008210.2
Iind00G0008210.3	isatis_indigotica	Iind00G0008210.3
Iind00G0008210.4	isatis_indigotica	Iind00G0008210.4
Iind00G0008210.5	isatis_indigotica	Iind00G0008210.5
Iind00G0008210.6	isatis_indigotica	Iind00G0008210.6
Iind00G0020020.1	isatis_indigotica	Iind00G0020020.1
Iind00G0020030.1	isatis_indigotica	Iind00G0020030.1
Iind00G0020040.1	isatis_indigotica	Iind00G0020040.1
Iind00G0020040.2	isatis_indigotica	Iind00G0020040.2
Iind00G0020040.3	isatis_indigotica	Iind00G0020040.3
Iind00G0020040.4	isatis_indigotica	Iind00G0020040.4
Iind00G0020040.5	isatis_indigotica	Iind00G0020040.5
Iind00G0020040.6	isatis_indigotica	Iind00G0020040.6
Iind00G0031690.1	isatis_indigotica	Iind00G0031690.1
Iind00G0031690.2	isatis_indigotica	Iind00G0031690.2
Iind00G0031690.3	isatis_indigotica	Iind00G0031690.3
Iind00G0031690.4	isatis_indigotica	Iind00G0031690.4
Iind04G0030440.1	isatis_indigotica	Iind04G0030440.1
Iind05G0016010.1	isatis_indigotica	Iind05G0016010.1
Iind05G0038860.1	isatis_indigotica	Iind05G0038860.1