PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
AagrBONNSc2ySwM_117G0007830 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0007830
AagrBONNSc2ySwM_117G0007890 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0007890
AagrBONNSc2ySwM_117G0011070 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0011070
AagrBONNSc2ySwM_117G0011210 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0011210
AagrBONNSc2ySwM_117G0014880 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0014880
AagrBONNSc2ySwM_117G0016160 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0016160
AagrBONNSc2ySwM_117G0020190 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0020190
AagrBONNSc2ySwM_117G0022170 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0022170
AagrBONNSc2ySwM_117G0023080 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0023080
AagrBONNSc2ySwM_117G0023140 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0023140
AagrBONNSc2ySwM_117G0027740 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0027740
AagrBONNSc2ySwM_117G0028210 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0028210
AagrBONNSc2ySwM_117G0032580 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0032580
AagrBONNSc2ySwM_117G0034420 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0034420
AagrBONNSc2ySwM_117G0034560 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0034560
AagrBONNSc2ySwM_117G0040510 anthoceros_agrestis_bonn AagrBONNSc2ySwM_117G0040510
AagrBONNSc2ySwM_228G0008940 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0008940
AagrBONNSc2ySwM_228G0012820 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0012820
AagrBONNSc2ySwM_228G0016310 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0016310
AagrBONNSc2ySwM_228G0016440 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0016440
AagrBONNSc2ySwM_228G0016450 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0016450
AagrBONNSc2ySwM_228G0016520 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0016520
AagrBONNSc2ySwM_228G0016530 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0016530
AagrBONNSc2ySwM_228G0019060 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0019060
AagrBONNSc2ySwM_228G0021790 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0021790
AagrBONNSc2ySwM_228G0022450 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0022450
AagrBONNSc2ySwM_228G0035250 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0035250
AagrBONNSc2ySwM_228G0041180 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0041180
AagrBONNSc2ySwM_228G0041640 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0041640
AagrBONNSc2ySwM_228G0048930 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0048930