PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
AagrBONNSc2ySwM_228G0049810 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0049810
AagrBONNSc2ySwM_228G0052760 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0052760
AagrBONNSc2ySwM_228G0057020 anthoceros_agrestis_bonn AagrBONNSc2ySwM_228G0057020
AagrBONNSc2ySwM_340G0000040 anthoceros_agrestis_bonn AagrBONNSc2ySwM_340G0000040
AagrBONNSc2ySwM_340G0000070 anthoceros_agrestis_bonn AagrBONNSc2ySwM_340G0000070
AagrBONNSc2ySwM_340G0000100 anthoceros_agrestis_bonn AagrBONNSc2ySwM_340G0000100
AagrBONNSc2ySwM_340G0000200 anthoceros_agrestis_bonn AagrBONNSc2ySwM_340G0000200
AagrBONNSc2ySwM_344G0005700 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005700
AagrBONNSc2ySwM_344G0005710 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005710
AagrBONNSc2ySwM_344G0005730 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005730
AagrBONNSc2ySwM_344G0005740 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005740
AagrBONNSc2ySwM_344G0005780 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005780
AagrBONNSc2ySwM_344G0005800 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005800
AagrBONNSc2ySwM_344G0005810 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0005810
AagrBONNSc2ySwM_344G0013890 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0013890
AagrBONNSc2ySwM_344G0016670 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0016670
AagrBONNSc2ySwM_344G0023930 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0023930
AagrBONNSc2ySwM_344G0023960 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0023960
AagrBONNSc2ySwM_344G0025540 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0025540
AagrBONNSc2ySwM_344G0025640 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0025640
AagrBONNSc2ySwM_344G0041050 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0041050
AagrBONNSc2ySwM_344G0041860 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0041860
AagrBONNSc2ySwM_344G0044350 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0044350
AagrBONNSc2ySwM_344G0053210 anthoceros_agrestis_bonn AagrBONNSc2ySwM_344G0053210
AagrBONNSc2ySwM_362G0003200 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0003200
AagrBONNSc2ySwM_362G0003230 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0003230
AagrBONNSc2ySwM_362G0009370 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0009370
AagrBONNSc2ySwM_362G0010640 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0010640
AagrBONNSc2ySwM_362G0019850 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0019850
AagrBONNSc2ySwM_362G0024410 anthoceros_agrestis_bonn AagrBONNSc2ySwM_362G0024410