PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT190 SQE37 CAS726
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT3593 SMO1/SMO2208 CPI118 CYP51G1179 FK18 HYD122 DWF7106 DWF55 DWF128
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Basal angiosperms (2224)
Current lineage filter: Basal angiosperms. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits0
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits2224
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Brasenia schreberi
Annona cherimola
Cinnamomum kanehirae
Cinnamomum camphora
Chloranthus sessilifolius
Amborella trichopoda
Piper nigrum
Aristolochia contorta
Nymphaea colorata
Liriodendron chinense
Lineage Summary
Basal angiosperms
2224
Module Gene List
Reset
GeneSpeciesProtein ID
AtriAmTr_v1.0_scaffold010100260940.1 amborella_trichopoda AtriAmTr_v1.0_scaffold010100260940.1
AtriAmTr_v1.0_scaffold027640264290.1 amborella_trichopoda AtriAmTr_v1.0_scaffold027640264290.1
AtriAmTr_v1.0_scaffold029860264620.1 amborella_trichopoda AtriAmTr_v1.0_scaffold029860264620.1
AtriAmTr_v1.0_scaffold051970267700.1 amborella_trichopoda AtriAmTr_v1.0_scaffold051970267700.1
annona_cherimola_Anche102Chr1g0045050.1 annona_cherimola annona_cherimola_Anche102Chr1g0045050.1
annona_cherimola_Anche102Chr1g0045060.1 annona_cherimola annona_cherimola_Anche102Chr1g0045060.1
annona_cherimola_Anche102Chr1g0045290.1 annona_cherimola annona_cherimola_Anche102Chr1g0045290.1
annona_cherimola_Anche102Chr1g0045530.1 annona_cherimola annona_cherimola_Anche102Chr1g0045530.1
annona_cherimola_Anche102Chr1g0046520.1 annona_cherimola annona_cherimola_Anche102Chr1g0046520.1
annona_cherimola_Anche102Chr1g0054200.1 annona_cherimola annona_cherimola_Anche102Chr1g0054200.1
annona_cherimola_Anche102Chr1g0054300.1 annona_cherimola annona_cherimola_Anche102Chr1g0054300.1
annona_cherimola_Anche102Chr1g0067740.1 annona_cherimola annona_cherimola_Anche102Chr1g0067740.1
annona_cherimola_Anche102Chr1g0069180.1 annona_cherimola annona_cherimola_Anche102Chr1g0069180.1
annona_cherimola_Anche102Chr1g0071710.1 annona_cherimola annona_cherimola_Anche102Chr1g0071710.1
annona_cherimola_Anche102Chr1g0085220.1 annona_cherimola annona_cherimola_Anche102Chr1g0085220.1
annona_cherimola_Anche102Chr1g0085910.1 annona_cherimola annona_cherimola_Anche102Chr1g0085910.1
annona_cherimola_Anche102Chr1g0090100.1 annona_cherimola annona_cherimola_Anche102Chr1g0090100.1
annona_cherimola_Anche102Chr1g0110350.1 annona_cherimola annona_cherimola_Anche102Chr1g0110350.1
annona_cherimola_Anche102Chr1g0116560.1 annona_cherimola annona_cherimola_Anche102Chr1g0116560.1
annona_cherimola_Anche102Chr1g0117070.1 annona_cherimola annona_cherimola_Anche102Chr1g0117070.1
annona_cherimola_Anche102Chr2g0021450.1 annona_cherimola annona_cherimola_Anche102Chr2g0021450.1
annona_cherimola_Anche102Chr2g0021540.1 annona_cherimola annona_cherimola_Anche102Chr2g0021540.1
annona_cherimola_Anche102Chr2g0037000.1 annona_cherimola annona_cherimola_Anche102Chr2g0037000.1
annona_cherimola_Anche102Chr2g0037320.1 annona_cherimola annona_cherimola_Anche102Chr2g0037320.1
annona_cherimola_Anche102Chr2g0037330.1 annona_cherimola annona_cherimola_Anche102Chr2g0037330.1
annona_cherimola_Anche102Chr2g0037840.1 annona_cherimola annona_cherimola_Anche102Chr2g0037840.1
annona_cherimola_Anche102Chr2g0045510.1 annona_cherimola annona_cherimola_Anche102Chr2g0045510.1
annona_cherimola_Anche102Chr2g0050220.1 annona_cherimola annona_cherimola_Anche102Chr2g0050220.1
annona_cherimola_Anche102Chr2g0050620.1 annona_cherimola annona_cherimola_Anche102Chr2g0050620.1
annona_cherimola_Anche102Chr2g0050730.1 annona_cherimola annona_cherimola_Anche102Chr2g0050730.1