PlantSME Plant secondary metabolism enzyme database
Steroid portable pathway

Steroid portable pathway

Category：Steroid pathway

Steroid pathway definition imported from the 2026-05-17 portable BLAST/HMM package.

Representative Steroid Reaction Route
Squalene to phytosterols and brassinosteroid branch. The steroid route starts from triterpenoid precursors, proceeds through squalene, 2,3-oxidosqualene, and cycloartenol, and then branches toward phytosterols and brassinosteroids; long branches are shown as curated modules.
3 curated steps/modules
Sterol Scaffold Formation
01
Substrate
Farnesyl diphosphate
C15H28O7P2
C15 prenyl-OPP
Squalene synthesis, epoxidation, and cyclization
SQS/FDFT1638 SQE185 CAS2570
Product
Cycloartenol
C30H50O
tetracyclic sterol nucleus with cyclopropyl side
SQS/SQE/CAS convert FPP-derived linear triterpenes into the plant sterol core.
02
Substrate
Cycloartenol-series intermediates
C28-C30 sterols
tetracyclic sterol nucleus
Demethylation, reduction, and side-chain remodeling
SMT1/SMT2/SMT31757 SMO1/SMO21119 CPI1170 CYP51G1313 FK164 HYD1184 DWF71136 DWF5419 DWF1227
Product
Phytosterols
C28H48O / C29H50O
sterol nucleus-C8/C9 side chain
This segment converts cycloartenol-series intermediates into phytosterol pools such as sitosterol and campesterol.
Brassinosteroid Branch
Lineage Distribution
Assignments under this module are distributed across the following plant lineages.
All Lineages Bryophytes (9925)
Current lineage filter: Bryophytes. All species, family, module, and gene statistics below have been narrowed to this lineage.
Algae
Hits0
Bryophytes
Hits9925
Lycophytes/Ferns
Hits0
Gymnosperms
Hits0
Basal angiosperms
Hits0
Monocots
Hits0
Eudicots
Hits0
Species Distribution
Bryum knowltonii
Anthoceros agrestis Oxford
Funaria hygrometrica
Buxbaumia aphylla
Anthoceros punctatus
Calliergon cordifolium
Archidium alternifolium
Fossombronia
Fissidens javanicus
Andreaea rupestris
Lineage Summary
Bryophytes
9925
Module Gene List
Reset
GeneSpeciesProtein ID
Gackstroemia6099430145290 gackstroemia Gackstroemia6099430145290
Gackstroemia6102100146800 gackstroemia Gackstroemia6102100146800
Gackstroemia6114500152520 gackstroemia Gackstroemia6114500152520
Gackstroemia6139600163250 gackstroemia Gackstroemia6139600163250
Gackstroemia6149490168320 gackstroemia Gackstroemia6149490168320
Gackstroemia6149490168330 gackstroemia Gackstroemia6149490168330
Gackstroemia6163910175590 gackstroemia Gackstroemia6163910175590
Gackstroemia6169790178100 gackstroemia Gackstroemia6169790178100
Gackstroemia6178170181880 gackstroemia Gackstroemia6178170181880
Gackstroemia6179650182640 gackstroemia Gackstroemia6179650182640
Gackstroemia6181470183430 gackstroemia Gackstroemia6181470183430
Gackstroemia6191050188220 gackstroemia Gackstroemia6191050188220
Gackstroemia6191180188250 gackstroemia Gackstroemia6191180188250
Gackstroemia6203030194080 gackstroemia Gackstroemia6203030194080
Gackstroemia6204150194530 gackstroemia Gackstroemia6204150194530
Gackstroemia6215770199280 gackstroemia Gackstroemia6215770199280
Gackstroemia6216110199410 gackstroemia Gackstroemia6216110199410
Gackstroemia6218380200230 gackstroemia Gackstroemia6218380200230
Gackstroemia6231820206210 gackstroemia Gackstroemia6231820206210
Gackstroemia6237440208550 gackstroemia Gackstroemia6237440208550
Gackstroemia6248030212770 gackstroemia Gackstroemia6248030212770
Gackstroemia6451050220040 gackstroemia Gackstroemia6451050220040
Gackstroemia6451060220060 gackstroemia Gackstroemia6451060220060
Gackstroemia6583940222790 gackstroemia Gackstroemia6583940222790
Gackstroemia6583950222800 gackstroemia Gackstroemia6583950222800
Gackstroemia6619160223390 gackstroemia Gackstroemia6619160223390
Gackstroemia6619170223410 gackstroemia Gackstroemia6619170223410
Gmag3716390003900 gackstroemia_magellanica Gmag3716390003900
Gmag3869790009350 gackstroemia_magellanica Gmag3869790009350
Gmag3929850011640 gackstroemia_magellanica Gmag3929850011640