SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
Mpol01G0017210.1	marchantia_polymorpha	Mpol01G0017210.1
marsdenia_tenacissima_EVM0001628.1	marsdenia_tenacissima	marsdenia_tenacissima_EVM0001628.1
marsdenia_tenacissima_EVM0008636.1	marsdenia_tenacissima	marsdenia_tenacissima_EVM0008636.1
marsdenia_tenacissima_EVM0015367.1	marsdenia_tenacissima	marsdenia_tenacissima_EVM0015367.1
Mrut01G0064610.1	medicago_ruthenica	Mrut01G0064610.1
Mrut03G0053490.1	medicago_ruthenica	Mrut03G0053490.1
Mrut04G0043110.1	medicago_ruthenica	Mrut04G0043110.1
Mrutctg18480020790.1	medicago_ruthenica	Mrutctg18480020790.1
Mtru01G0006160.1	medicago_truncatula	Mtru01G0006160.1
Mtru01G0006160.2	medicago_truncatula	Mtru01G0006160.2
Mtru02G0011740.1	medicago_truncatula	Mtru02G0011740.1
Mtru03G0057010.1	medicago_truncatula	Mtru03G0057010.1
Mtru03G0057010.2	medicago_truncatula	Mtru03G0057010.2
Mtru03G0060710.1	medicago_truncatula	Mtru03G0060710.1
Mtru04G0046500.1	medicago_truncatula	Mtru04G0046500.1
Mtru05G0018410.1	medicago_truncatula	Mtru05G0018410.1
Mtru06G0015520.1	medicago_truncatula	Mtru06G0015520.1
Mtru06G0015610.1	medicago_truncatula	Mtru06G0015610.1
Mtru07G0025880.1	medicago_truncatula	Mtru07G0025880.1
MdelGWHANWI000008130019080.1	megacarpaea_delavayi	MdelGWHANWI000008130019080.1
MdelGWHANWI000008140019090.1	megacarpaea_delavayi	MdelGWHANWI000008140019090.1
MdelGWHANWI000049720100880.1	megacarpaea_delavayi	MdelGWHANWI000049720100880.1
MdelGWHANWI000079270148250.1	megacarpaea_delavayi	MdelGWHANWI000079270148250.1
MdelGWHANWI000079300148260.1	megacarpaea_delavayi	MdelGWHANWI000079300148260.1
MdelGWHANWI000166890227060.5	megacarpaea_delavayi	MdelGWHANWI000166890227060.5
MdelGWHANWI000175570232300.1	megacarpaea_delavayi	MdelGWHANWI000175570232300.1
MdelGWHANWI000504900281870.1	megacarpaea_delavayi	MdelGWHANWI000504900281870.1
MpygGWHANWB000000020069880.1	megadenia_pygmaea	MpygGWHANWB000000020069880.1
MpygGWHANWB000000030073200.1	megadenia_pygmaea	MpygGWHANWB000000030073200.1
MpygGWHANWB000000050158580.1	megadenia_pygmaea	MpygGWHANWB000000050158580.1