SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
MpygGWHANWB000000050181120.1	megadenia_pygmaea	MpygGWHANWB000000050181120.1
MpygGWHANWB000000060209790.1	megadenia_pygmaea	MpygGWHANWB000000060209790.1
MpygGWHANWB000000060211520.1	megadenia_pygmaea	MpygGWHANWB000000060211520.1
melaleuca_alternifolia_scf7180000028550_gene_306	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000028550_gene_306
melaleuca_alternifolia_scf7180000036271_gene_113	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000036271_gene_113
melaleuca_alternifolia_scf7180000036750_gene_528	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000036750_gene_528
melaleuca_alternifolia_scf7180000036750_gene_88	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000036750_gene_88
melaleuca_alternifolia_scf7180000036828_gene_292	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000036828_gene_292
melaleuca_alternifolia_scf7180000039141_gene_396	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000039141_gene_396
melaleuca_alternifolia_scf7180000039141_gene_397	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000039141_gene_397
melaleuca_alternifolia_scf7180000039141_gene_398	melaleuca_alternifolia	melaleuca_alternifolia_scf7180000039141_gene_398
Mlonscaffold_5_length_432313370136320.1	mentha_longifolia	Mlonscaffold_5_length_432313370136320.1
Mlonscaffold_6_length_375374740144380.1	mentha_longifolia	Mlonscaffold_6_length_375374740144380.1
Mlonscaffold_6_length_375374740145800.1	mentha_longifolia	Mlonscaffold_6_length_375374740145800.1
mesembryanthemum_crystallinum_Mc01G00702	mesembryanthemum_crystallinum	mesembryanthemum_crystallinum_Mc01G00702
mesembryanthemum_crystallinum_Mc02G00735	mesembryanthemum_crystallinum	mesembryanthemum_crystallinum_Mc02G00735
mesembryanthemum_crystallinum_Mc02G01938	mesembryanthemum_crystallinum	mesembryanthemum_crystallinum_Mc02G01938
mesembryanthemum_crystallinum_Mc05G01951	mesembryanthemum_crystallinum	mesembryanthemum_crystallinum_Mc05G01951
Mesp6296910273970	mesoptychia_sp	Mesp6296910273970
MendS1100007940	mesotaenium_endlicherianum	MendS1100007940
mesua_ferrea_Mesfe423S24388_MESFER	mesua_ferrea	mesua_ferrea_Mesfe423S24388_MESFER
mesua_ferrea_Mesfe5S26030_MESFER	mesua_ferrea	mesua_ferrea_Mesfe5S26030_MESFER
Mhamcontig_1800114610	metzgeria_hamata	Mhamcontig_1800114610
Mhamcontig_2350183000	metzgeria_hamata	Mhamcontig_2350183000
Mhamcontig_650240790	metzgeria_hamata	Mhamcontig_650240790
Mcom08G0005100.1	micromonas_commoda	Mcom08G0005100.1
60873\|PACid:27403370	micromonas_sp_rcc299	60873\|PACid:27403370
Mpudscaffold12514_cov1810035980	mimosa_pudica	Mpudscaffold12514_cov1810035980
Mpudscaffold152_cov1430096200	mimosa_pudica	Mpudscaffold152_cov1430096200
Mpudscaffold1634_cov2240105460	mimosa_pudica	Mpudscaffold1634_cov2240105460