SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
physalis_grisea_Phygri02g026570.1	physalis_grisea	physalis_grisea_Phygri02g026570.1
physalis_grisea_Phygri06g016590.1	physalis_grisea	physalis_grisea_Phygri06g016590.1
physalis_grisea_Phygri07g018820.1	physalis_grisea	physalis_grisea_Phygri07g018820.1
physalis_grisea_Phygri08g006190.1	physalis_grisea	physalis_grisea_Phygri08g006190.1
physalis_grisea_Phygri10g004832.1	physalis_grisea	physalis_grisea_Phygri10g004832.1
physalis_grisea_Phygri11g022180.1	physalis_grisea	physalis_grisea_Phygri11g022180.1
physalis_pruinosa_Phypru02g026830.1	physalis_pruinosa	physalis_pruinosa_Phypru02g026830.1
physalis_pruinosa_Phypru06g017600.1	physalis_pruinosa	physalis_pruinosa_Phypru06g017600.1
physalis_pruinosa_Phypru07g019040.1	physalis_pruinosa	physalis_pruinosa_Phypru07g019040.1
physalis_pruinosa_Phypru08g006170.1	physalis_pruinosa	physalis_pruinosa_Phypru08g006170.1
physalis_pruinosa_Phypru10g004872.1	physalis_pruinosa	physalis_pruinosa_Phypru10g004872.1
physalis_pruinosa_Phypru11g022220.1	physalis_pruinosa	physalis_pruinosa_Phypru11g022220.1
Ppat14G0004550.1	physcomitrella_patens	Ppat14G0004550.1
Ppat14G0004560.1	physcomitrella_patens	Ppat14G0004560.1
Ppat19G0002270.1	physcomitrella_patens	Ppat19G0002270.1
Ppat19G0002270.2	physcomitrella_patens	Ppat19G0002270.2
PspPicochlorum_contig_190025610.1	picochlorum_sp	PspPicochlorum_contig_190025610.1
PspPicochlorum_contig_870068790.1	picochlorum_sp	PspPicochlorum_contig_870068790.1
PITA_000009606-RA	pinus_taeda	PITA_000009606-RA
PITA_000055112-RA	pinus_taeda	PITA_000055112-RA
PITA_000059364-RA	pinus_taeda	PITA_000059364-RA
PITA_000084147-RA	pinus_taeda	PITA_000084147-RA
PL03G0104380	piper_longum	PL03G0104380
PL04G0125080	piper_longum	PL04G0125080
PL04G0132090	piper_longum	PL04G0132090
PL04G0132100	piper_longum	PL04G0132100
Pnig02G0018360	piper_nigrum	Pnig02G0018360
Pnig02G0018420	piper_nigrum	Pnig02G0018420
pistacia_chinensis_KAJ0025374.1	pistacia_chinensis	pistacia_chinensis_KAJ0025374.1
pistacia_chinensis_KAJ0040453.1	pistacia_chinensis	pistacia_chinensis_KAJ0040453.1