SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
BAampscaffold_120056890	barbula_amplexifolia	BAampscaffold_120056890
BAampscaffold_30129820	barbula_amplexifolia	BAampscaffold_30129820
BAampscaffold_70210620	barbula_amplexifolia	BAampscaffold_70210620
BAampscaffold_90244880	barbula_amplexifolia	BAampscaffold_90244880
Bith1660059740	bartramia_ithyphylla	Bith1660059740
Bith1970098120	bartramia_ithyphylla	Bith1970098120
Bith2680159850	bartramia_ithyphylla	Bith2680159850
Bith610211000	bartramia_ithyphylla	Bith610211000
Bathy01g06810	bathycoccus_prasinos	Bathy01g06810
bauhinia_variegata_KAI4296496.1	bauhinia_variegata	bauhinia_variegata_KAI4296496.1
bauhinia_variegata_KAI4299214.1	bauhinia_variegata	bauhinia_variegata_KAI4299214.1
bauhinia_variegata_KAI4315103.1	bauhinia_variegata	bauhinia_variegata_KAI4315103.1
bauhinia_variegata_KAI4315104.1	bauhinia_variegata	bauhinia_variegata_KAI4315104.1
bauhinia_variegata_KAI4316577.1	bauhinia_variegata	bauhinia_variegata_KAI4316577.1
bauhinia_variegata_KAI4327310.1	bauhinia_variegata	bauhinia_variegata_KAI4327310.1
bauhinia_variegata_KAI4327311.1	bauhinia_variegata	bauhinia_variegata_KAI4327311.1
bauhinia_variegata_KAI4337091.1	bauhinia_variegata	bauhinia_variegata_KAI4337091.1
Btri1272030099450	bazzania_tridens	Btri1272030099450
Bfucscaffold1011_cov1260000900	begonia_fuchsioides	Bfucscaffold1011_cov1260000900
Bfucscaffold10926_cov1320012290	begonia_fuchsioides	Bfucscaffold10926_cov1320012290
Bfucscaffold1871_cov1610135690	begonia_fuchsioides	Bfucscaffold1871_cov1610135690
Bfucscaffold2089_cov1410158600	begonia_fuchsioides	Bfucscaffold2089_cov1410158600
Bfucscaffold2199_cov1690168720	begonia_fuchsioides	Bfucscaffold2199_cov1690168720
Bfucscaffold2383_cov1790190860	begonia_fuchsioides	Bfucscaffold2383_cov1790190860
Bfucscaffold2842_cov1270227640	begonia_fuchsioides	Bfucscaffold2842_cov1270227640
Bfucscaffold2842_cov1270227650	begonia_fuchsioides	Bfucscaffold2842_cov1270227650
Bfucscaffold3169_cov1320255510	begonia_fuchsioides	Bfucscaffold3169_cov1320255510
Bfucscaffold4227_cov1690319470	begonia_fuchsioides	Bfucscaffold4227_cov1690319470
Bfucscaffold850_cov1560454960	begonia_fuchsioides	Bfucscaffold850_cov1560454960
Bfucscaffold91298_cov1920475380	begonia_fuchsioides	Bfucscaffold91298_cov1920475380