PlantSME Plant secondary metabolism enzyme database
SQE

SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage
Detected in 773 of 789 public species; click a lineage to inspect its species list.
Algae
Bryophytes
Lycophytes/Ferns
Gymnosperms
Basal angiosperms
Monocots
Eudicots
Species Distribution
Fragaria ananassa
Fragaria chiloensis
Rosa multiflora
Gossypium raimondii
Related Modules
Steroid pathway
Pathway Position Map
Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.
Curated order
Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024
Sterol precursor formation
SQS/FDFT1 4389 SQE 4569 CAS 35857
Phytosterol backbone
SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689
Brassinosteroid branch
DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68
Family Gene List
GeneSpeciesProtein ID
Hvulchr4HG0019390.1 hordeum_vulgare Hvulchr4HG0019390.1
Hvulchr4HG0029590.1 hordeum_vulgare Hvulchr4HG0029590.1
Hvulchr4HG0029590.2 hordeum_vulgare Hvulchr4HG0029590.2
Hvulchr4HG0032930.1 hordeum_vulgare Hvulchr4HG0032930.1
Hvulchr4HG0032930.2 hordeum_vulgare Hvulchr4HG0032930.2
Hvulchr4HG0032930.3 hordeum_vulgare Hvulchr4HG0032930.3
Hvulchr4HG0032930.4 hordeum_vulgare Hvulchr4HG0032930.4
Hvulchr4HG0032930.5 hordeum_vulgare Hvulchr4HG0032930.5
Hvulchr4HG0032930.7 hordeum_vulgare Hvulchr4HG0032930.7
Hlup000015F0016410.1 humulus_lupulus Hlup000015F0016410.1
Hlup000326F0145570.1 humulus_lupulus Hlup000326F0145570.1
Hlup000767F0259810.1 humulus_lupulus Hlup000767F0259810.1
Hlup001166F0343690.1 humulus_lupulus Hlup001166F0343690.1
Hlup001190F0347710.1 humulus_lupulus Hlup001190F0347710.1
Hlup001498F0404520.1 humulus_lupulus Hlup001498F0404520.1
Hlup001523F0409000.1 humulus_lupulus Hlup001523F0409000.1
Hlup002547F0546160.1 humulus_lupulus Hlup002547F0546160.1
Hlup002547F0546170.1 humulus_lupulus Hlup002547F0546170.1
Hlup002566F0548370.1 humulus_lupulus Hlup002566F0548370.1
Hlup005777F0796160.1 humulus_lupulus Hlup005777F0796160.1
Hlup005777F0796170.1 humulus_lupulus Hlup005777F0796170.1
hydrangea_macrophylla_Hma1.2p1_0001F.1_g001680 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_0001F.1_g001680
hydrangea_macrophylla_Hma1.2p1_0156F.1_g068720 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_0156F.1_g068720
hydrangea_macrophylla_Hma1.2p1_0435F.1_g152420 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_0435F.1_g152420
hydrangea_macrophylla_Hma1.2p1_0477F.1_g161110 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_0477F.1_g161110
hydrangea_macrophylla_Hma1.2p1_0708F.1_g207150 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_0708F.1_g207150
hydrangea_macrophylla_Hma1.2p1_1230F.1_g268760 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_1230F.1_g268760
hydrangea_macrophylla_Hma1.2p1_2001F.1_g310630 hydrangea_macrophylla hydrangea_macrophylla_Hma1.2p1_2001F.1_g310630
HvarHygva1541230080540 hygroamblystegium_varium HvarHygva1541230080540
HvarHygva18840285810 hygroamblystegium_varium HvarHygva18840285810