SQE

Triterpenoid/sterol-precursor shared module: SQS/SQE/OSC-family cyclases build the triterpenoid scaffold feeding sterol biosynthesis; overlap between terpenoid and steroid contexts is expected.

Atlas summary family SQE.

Lineage Coverage

Detected in 773 of 789 public species; click a lineage to inspect its species list.

Species Distribution

Related Modules

Pathway Position Map

Pathways are arranged by literature-curated biosynthetic stages and highlight the current enzyme family; branched pathways are grouped by stage rather than forced into one linear reaction chain.

Curated order

Steroid pathway 4569 current-family members Du et al. 2022; Zebosi et al. 2024

Sterol precursor formation

SQS/FDFT1 4389 SQE 4569 CAS 35857

Phytosterol backbone

SMT1/SMT2/SMT3 27781 SMO1/SMO2 4067 CPI1 1261 CYP51G1 190 FK 1234 HYD1 1364 DWF7 1524 DWF5 888 DWF1 1689

Brassinosteroid branch

DET2 1316 DWF4/CYP90B1 290 CPD/CYP90A1 103 ROT3/CYP90C1 193 CYP90D1 142 BR6OX1/CYP85A1 40 BR6OX2/CYP85A2 68

Family Gene List

Gene	Species	Protein ID
HvarHygva7900453690	hygroamblystegium_varium	HvarHygva7900453690
Hlur1316640011830	hygrohypnum_luridum	Hlur1316640011830
Hlur1321720188790	hygrohypnum_luridum	Hlur1321720188790
Hcur1316640011830	hypnum_curvifolium	Hcur1316640011830
Hcur1321720011660	hypnum_curvifolium	Hcur1321720011660
Hela478360103740	hypopterygium_elatum	Hela478360103740
Hjapcontig_6440224750	hypopterygium_japonicum	Hjapcontig_6440224750
Hjapcontig_9670348040	hypopterygium_japonicum	Hjapcontig_9670348040
ilex_asprella_Ilex_004339-T1	ilex_asprella	ilex_asprella_Ilex_004339-T1
ilex_asprella_Ilex_024188-T1	ilex_asprella	ilex_asprella_Ilex_024188-T1
ilex_asprella_Ilex_029513-T1	ilex_asprella	ilex_asprella_Ilex_029513-T1
ilex_asprella_Ilex_034946-T1	ilex_asprella	ilex_asprella_Ilex_034946-T1
ilex_asprella_Ilex_035055-T1	ilex_asprella	ilex_asprella_Ilex_035055-T1
ilex_asprella_Ilex_044388-T1	ilex_asprella	ilex_asprella_Ilex_044388-T1
ilex_asprella_Ilex_044389-T1	ilex_asprella	ilex_asprella_Ilex_044389-T1
ilex_asprella_Ilex_045909-T1	ilex_asprella	ilex_asprella_Ilex_045909-T1
ilex_asprella_Ilex_049784-T1	ilex_asprella	ilex_asprella_Ilex_049784-T1
ilex_asprella_Ilex_049785-T1	ilex_asprella	ilex_asprella_Ilex_049785-T1
ilex_latifolia_GWHPBIST000345	ilex_latifolia	ilex_latifolia_GWHPBIST000345
ilex_latifolia_GWHPBIST001016	ilex_latifolia	ilex_latifolia_GWHPBIST001016
ilex_latifolia_GWHPBIST001430	ilex_latifolia	ilex_latifolia_GWHPBIST001430
ilex_latifolia_GWHPBIST004261	ilex_latifolia	ilex_latifolia_GWHPBIST004261
ilex_latifolia_GWHPBIST008272	ilex_latifolia	ilex_latifolia_GWHPBIST008272
ilex_latifolia_GWHPBIST013587	ilex_latifolia	ilex_latifolia_GWHPBIST013587
ilex_latifolia_GWHPBIST015501	ilex_latifolia	ilex_latifolia_GWHPBIST015501
ilex_latifolia_GWHPBIST023490	ilex_latifolia	ilex_latifolia_GWHPBIST023490
ilex_latifolia_GWHPBIST024488	ilex_latifolia	ilex_latifolia_GWHPBIST024488
ilex_latifolia_GWHPBIST026621	ilex_latifolia	ilex_latifolia_GWHPBIST026621
ilex_latifolia_GWHPBIST031986	ilex_latifolia	ilex_latifolia_GWHPBIST031986
ilex_latifolia_GWHPBIST031987	ilex_latifolia	ilex_latifolia_GWHPBIST031987